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Knee Injury clinical trials

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NCT ID: NCT02649322 Completed - Knee Injury Clinical Trials

Needleless Jet Injected (J-Tip) Lidocaine in Children Undergoing Regional Anesthesia Prior to Knee Arthroscopy

Start date: September 3, 2015
Phase: N/A
Study type: Interventional

Purpose of this study is to investigate the pain outcomes and satisfaction of pain relief for pediatric patients receiving needleless jet-injected (J-Tip) lidocaine prior to regional anesthesia with femoral and/or sciatic nerve block and general anesthesia for arthroscopic knee surgery compared to femoral nerve block and/or sciatic nerve block with needle injected lidocaine prior to regional and general anesthesia.

NCT ID: NCT02637505 Completed - Cartilage Injury Clinical Trials

Norwegian Cartilage Project - Microfracture

Start date: January 2016
Phase: N/A
Study type: Interventional

114 patients between 18 and 50 years with an isolated focal cartilage defect in the knee will be randomized to either receive arthroscopic microfracture or arthroscopic debridement. Both groups will then undergo a systematic physiotherapy training regime for 6-9 months. The groups will then be compared for results, after 3, 6, 12 and 24 months, by using validated patient reported outcome scores (Lysholm, KOOS, Tegner) and EQ5D as well as clinical examination and radiological findings at 2 years (MRI).

NCT ID: NCT02636881 Recruiting - Cartilage Injury Clinical Trials

Autologous Cartilage Implantation vs Arthroscopic Debridement

ACI
Start date: April 2016
Phase: N/A
Study type: Interventional

82 patients aged 18-49 years with an isolated focal cartilage defect in the knee will be randomized to either receive autologous cartilage implantation or arthroscopic debridement. Both groups will then undergo a systematic physiotherapy training regime for 6-9 months. The Groups will then be compared for results, after 3, 6, 12 and 24 months, by using validated patient reported outcome scores (Lysholm, KOOS, Tegner) and EQ5D (European Quality of Life 5 dimensions) as well as clinical examination and radiological findings at 2 years (MRI).

NCT ID: NCT02148172 Completed - Clinical trials for Anterior Cruciate Ligament Injury

Optimizing Plyometric Training for Functional Recovery Post-ACL Reconstruction

Start date: January 2014
Phase: N/A
Study type: Interventional

While surgical anterior cruciate ligament reconstruction (ACLR) of the knee restores passive stability, studies are showing consistently poor long-term outcomes. Unusually high risks of early-onset osteoarthritis and re-injury, and low rate of return to sport following ACLR all seem to be related to a chronic tendency to land stiff-legged from a jump or hop, which itself may be due to fear of re-injury. Decreased knee bending for force absorption simultaneously decreases performance level and increases risk for injury and arthritic changes. The purpose of the proposed study is to compare a current best-practice plyometric training program to one utilizing body weight support to increase repetition and improve performance in the initial phases. The investigators hypothesize that we will see larger improvements in absorptive capacity of the knee and better confidence in activity immediately following body weight support training, as well as improved retention of training effects after a two-month period.

NCT ID: NCT02065518 Completed - Knee Injury Clinical Trials

Electromyostimulation and Strength Walking for Knee Injuries

KI
Start date: March 2014
Phase: N/A
Study type: Interventional

The purpose of this project is to compare three treatment regimens for knee injury to the standard rehabilitation protocol: 1) NMES, 2) graduated strength walking (via a weighted vest), and 3) NMES combined with graduated strength walking. Each treatment arm will be supplemented by the standard of care and compared to a group who receive the standard rehabilitation only. The Study will compare the effects of NMES, Strength Walking and combined NMES/ Strength Walking on strength, mobility, symptomatology, and Quality of Life (QOL) in military members with knee injury to a standard rehabilitation protocol program only. All groups will participate in standard rehabilitation protocol. The groups will be assessed over 18 weeks to compare main and interactive effects over time.

NCT ID: NCT02052856 Completed - ACL Injury Clinical Trials

Anterior Cruciate Ligament (ACL) Tunnel Widening Comparing All-inside and Interference Screw Fixation Technique

Start date: December 2012
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the incidence and degree of bone tunnel widening between two groups who have undergone anterior cruciate ligament reconstructive surgery. The two groups have undergone different graft fixation methods: an interference screw/suspensory button fixation hybrid technique, and an all-inside suspensory method fixation. Tunnels are created at the time of surgery for graft placement and fixation, but have been known to enlarge post-operatively. Little has been studied on the relatively new all-inside technique. X-rays of the operative knee will be used to assess tunnel width. Secondary outcomes will include clinical evaluation and outcome scoring questionnaires

NCT ID: NCT01971645 Completed - Knee Injury Clinical Trials

Decadron as Adjuvant in Femoral Nerve Blocks in Knee Arthroscopy

Start date: July 2014
Phase: Phase 3
Study type: Interventional

If preservative-free dexamethasone 0.1 mg/kg (max dose 4 mg) is added to ropivacaine 0.5% 2 mg/kg (max dose 100 mg), then post-PACU opioid consumption will be reduced by 33%.

NCT ID: NCT01950208 Completed - Knee Injury Clinical Trials

The Munich Knee Questionnaire - Development and Validation

MKQ
Start date: August 2012
Phase: N/A
Study type: Observational

the purpose of this study is to develop and validate a new PRO measurement tool for the knee joint, the so-called Munich Knee Questionnaire (MKQ), allowing for a qualitative self-assessment of the Knee Injury and Osteoarthritis Outcome Score (KOOS), the International Knee Documentation Committee (IKDC), the Lysholm Knee Score, the Western Ontario Meniscal Evaluation Tool (WOMET) and the Tegner Score.

NCT ID: NCT01382173 Terminated - Knee Osteoarthritis Clinical Trials

Monitoring Of Helsingborg Acute Knee Injuries (MOHAK)

Start date: March 2012
Phase:
Study type: Observational

Using magnetic resonance imaging (MRI), laboratory analyses and patient reported outcomes, the overall aim of this study is to investigate structural injuries and biochemical alterations in the acutely injured knee and to relate these findings to clinical outcomes at various time points.

NCT ID: NCT00984594 Terminated - Knee Injury Clinical Trials

Evaluation of a Composite Cancellous and Demineralized Bone Plug (CR-Plug) for Repair of Knee Osteochondral Defects

Start date: January 2009
Phase: Phase 3
Study type: Interventional

The objective of this study is to determine how effective a plug made out of human bone (called "CR-Plug") will be in the treatment of smaller, focal defects (like the injury the patient has to their knee).