Pregabalin Premedication for Knee Arthroscopy

Status Not yet recruiting

Clinical Trial Summary

Outpatient arthroscopic knee surgery can be performed with general or regional anesthesia. Recent data suggest that spinal and epidural anesthesia require longer discharge times than the newer shorter-acting general anesthetic drugs. Ideal premedication drug should relieve anxiety, produce amnesia and sedation, decrease secretions, prevent nausea and vomiting, have dose sparing effect on the anaesthetic drugs, and suppress pressor response to laryngoscopy and intubation. Recently, gabapentin and pregabalin were suggested as pre-operative drugs to decrease anxiety, stress response to laryngoscopy and post operative pain.

Clinical Trial Description

112 patients undergoing elective knee arthroscopy will randomly divided into two equal groups, 56 patients each. All patients will receive premedication one hour before the procedure. PG group will receive 150 mg pregabalin and C group will receive placebo. All patients will receive total intravenous anesthesia to achieve optimum working conditions. Intra-operative total amount of anesthetics will be compared in both groups. ;

Study Design

Related Conditions & MeSH terms

Knee Arthroscopy

Clinical Trial Details

NCT number	NCT03926000
Study type	Interventional
Source	Menoufia University
Contact
Status	Not yet recruiting
Phase	N/A
Start date	June 2019
Completion date	December 2019

View Details

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