Clinical Trials Logo

Knee Arthroplasty clinical trials

View clinical trials related to Knee Arthroplasty.

Filter by:

NCT ID: NCT03035435 Completed - Knee Arthroplasty Clinical Trials

Fast-track Rehabilitation After Total Knee or Hip Arthroplasty

Start date: January 2016
Phase: N/A
Study type: Observational

In the last years, a lot of surgical fast track programs (SFTP) have been created and developed. This is due to the steady growing number of interventions on knee and hip; after the surgical treatment, a period of physical rehabilitation (PR) is established to be useful and effective, it usually takes 2-3 weeks. The recovery of strength, range of motion (ROM), independence, the reduction of pain and disability are the aims of PR. With the SFTP and a specific rehabilitation program named fast track rehabilitation (FTR) these times can be reduced. First of all because the length of stay (LOS) it's also caused by organizational problems of the hospitals, not only for the factors related to the patient. It's already been demonstrated that an early mobilization decreases the risk of thromboembolic complications and of pain, furthermore an early rehabilitation increase the patient autonomy and reduces the lost of residual abilities. Moreover a PR program studied for fast track patient will reduce minimum by a 50% the LOS in hospital, decreasing so the sanitary efforts that are always a problem for all the countries. The aim of this study is therefore to propose a fast track rehabilitation program based on an 8 days program for hip and knee arthroplasty being operated with an SFTP.

NCT ID: NCT03025594 Recruiting - Pain Management Clinical Trials

Gonyautoxins Local Periarticular Injection for Pain Management After Total Knee Arthroplasty

Toxin
Start date: January 2017
Phase: Phase 3
Study type: Interventional

The aim of this study is to demostrate the eficcacy in pain control management after total knee arthroplasty of Gonyautoxin. Local administration during surgery of Gonyautoxin before wound closure can achieved better pain control and lower morphin use during hospital stay compared to local administration of chirocaine, ketorolac and epinephrine

NCT ID: NCT02944409 Recruiting - Knee Arthroplasty Clinical Trials

VEGA System® Study in the Total Knee Arthroplasty

Start date: July 1, 2016
Phase:
Study type: Observational

This post-market clinical follow-up study intends to investigate long-term functionality of the VEGA System®. The design of the VEGA System® is meant to provide the patient with more knee mobility compared to their pre-operative state.The endpoint is the revision of at least one of the prosthesis components

NCT ID: NCT02934802 Recruiting - Knee Arthroplasty Clinical Trials

Non-Interventional Consecutive and Prospective Study of e.Motion® PS Pro Prosthesis in the Total Knee Artroplasty

Start date: May 26, 2016
Phase:
Study type: Observational

This post-market clinical follow-up study intends to investigate the survival rate at 5 years of the e.motion® PS Pro System.

NCT ID: NCT02791477 Active, not recruiting - Knee Arthroplasty Clinical Trials

Functional Results With Attune Fixed Bearing Posterior Stabilized Knee Arthroplasty (A-16)

Start date: May 2016
Phase: N/A
Study type: Interventional

Functional results with Attune Fixed Bearing Posterior Stabilized total knee arthroplasty evaluated with KOOS. A prospective longitudinal cohort study with repetitive measurements 6 weeks, 3, 6, 12 and 24 months postoperative.

NCT ID: NCT02581683 Completed - Knee Arthroplasty Clinical Trials

Magnesium Sulfate in Adductor Canal Blocks

Start date: September 2015
Phase: Phase 4
Study type: Interventional

Proper analgesia after total knee arthroplasty (TKA) is important for encouraging early ambulation, which can facilitate improved patient outcomes and early hospital discharge. For pain control after TKA, adductor canal blocks (ACBs) improve upon the gold standard femoral nerve blocks (FNBs) since they do not cause as much quadriceps muscle weakening, while providing equivalent analgesia. Multimodal analgesia has become commonplace as a method of superior pain control with fewer side effects. Magnesium sulfate as an adjuvant to FNB local anesthetics can improve pain control after surgery; however, it also prolongs time to ambulation. There are no reports on the effect of magnesium sulfate in ACBs on analgesia after TKA. Thus the purpose of this randomized, double-blind, controlled trial is to determine whether magnesium sulfate given with local anesthetics via ACB can prolong analgesia, reduce pain scores and opioid consumption, and increase mobilization in TKA patients.

NCT ID: NCT02540070 Recruiting - Osteoarthritis Clinical Trials

Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty

Start date: August 2014
Phase: Phase 3
Study type: Interventional

Patients undergoing primary total knee replacement will receive either motor sparing knee block to be performed by anesthesia or periarticular local anesthetic infiltration at the end of surgery by surgeons to assess pain relief as well as capacity to ambulate early. The motor sparing knee block will be performed prior to surgery using ultrasonography and the effect of adding dexmedetomidine, an alpha 2 agonist to the injectate with regards to prolonging the duration of analgesia will be assessed.

NCT ID: NCT02496377 Completed - Knee Arthroplasty Clinical Trials

Cross Iron (Comparative Randomized Oral Versus Systemic IRON)

Cross Iron
Start date: August 29, 2014
Phase: N/A
Study type: Interventional

Patients were recruited at the scheduled preoperative visit for hip or knee arthroplasty. If the haemoglobin (Hb) level was below 13 g/dl with no contraindication to iron supplementation the patients were randomized to the oral or intravenous (IV) group. The oral group received 160 mg ferrous glycine sulfate daily during the month prior surgery, associated with 3 epoetin alpha (EPO) injections (40 000 IU subcutaneous on day - 21, day - 14 and day-7). The IV group received ferric carboxymaltose 1000 mg IV in 15 minutes one month before surgery, associated with 3 EPO injections. Primary efficacy endpoint was the change in Hb level from the day of the preoperative visit to the day before surgery (day-1). Secondary endpoints comprised the Hb level on day 3 and 5 after surgery, allogenic transfusion during and after surgery, and the change in iron indices from the day of the preoperative visit to day - 1.

NCT ID: NCT02413996 Completed - Osteoarthritis Clinical Trials

Effects of Virtual Reality Rehabilitation in Patients With Total Knee Arthroplasty

Start date: September 2014
Phase: N/A
Study type: Interventional

The aim of this study is to assess the efficacy of virtual rehabilitation through the Virtual Reality Rehabilitation System (VRRS) versus traditional rehabilitation improving the functional outcomes after primary Total Knee Arthroplasty (TKA).

NCT ID: NCT02339831 Completed - Knee Arthroplasty Clinical Trials

Active Versus Passive Motion Device Following Knee Replacement Surgery

Start date: March 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how well an active motion device, Camoped, works compared to a continuous passive motion device, CPM, for rehabilitation after partial or total knee replacement. It is hypothesized that the Camoped active motion device will provide outcomes equal to or superior than the CPM. Patients undergoing either partial or total knee replacement will be given the opportunity to participate. If they elect to participate, preoperative data will be collected including demographics, measures of strength, balance and knee bending, as well as surveys regarding current physical and mental health, as well as knee function. After surgery, patients will be randomly selected to receive either the Camoped or the CPM for use during their rehabilitation. After discharge, participants will be asked to maintain a daily diary tracking their use of the assigned device, as well as their daily pain levels. At a visit 4 weeks after surgery, participants will be asked to complete a series of surveys pertaining to their health and knee function, as well as to perform tests of strength, balance and knee bending. These results will be used to determine if one device produces superior rehabilitation results following total or partial knee replacement surgery.