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Knee Arthropathy clinical trials

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NCT ID: NCT06298721 Recruiting - Surgery Clinical Trials

Improving Total Knee Arthroplasty Dissatisfaction Through a Personalized Approach Focusing on PROMs Phenotypes

Start date: March 12, 2024
Phase: N/A
Study type: Interventional

This study is a randomized controlled trial to assess whether the implementation of a TKA Personalized Outcome Prediction Tool to set expectation, in addition to targeted interventions to address patients with poor baseline mental health and poor physical function, improves satisfaction at 1-year (when compared to standard of care).

NCT ID: NCT06203483 Recruiting - Knee Osteoarthritis Clinical Trials

Ultrasound Guıded Adductor Canal Block vs Perıcapsular Nerve Group Block in Knee Artroplasty

Start date: January 20, 2024
Phase: N/A
Study type: Interventional

Knee arthroplasty surgery numbers are increasing depending on joint deformities and cartilage degenerations. Severe postoperative pain may occur in these patients due to surgery and the placed prosthesis. The aim of study is to compare the effectiveness of AKB and PENG block for postoperative analgesia management after knee arthroplasty.

NCT ID: NCT06182059 Recruiting - Knee Arthropathy Clinical Trials

Persistent Post Surgical Pain After Total Knee Arthroplasty

Start date: January 12, 2024
Phase: N/A
Study type: Interventional

Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this latter technique may reduce persistent postoperative pain six months after surgery

NCT ID: NCT06181097 Recruiting - Knee Arthropathy Clinical Trials

Routine Use of Negative Pressure Wound Therapy THR TKR RCT

Start date: December 11, 2023
Phase: N/A
Study type: Interventional

Negative pressure wound therapy (NPWT) for post total joint arthroplasty incisions has demonstrated benefits in reducing wound complications. A prospective randomized trial will be conducted including 40 patients who will undergo total knee and total hip arthroplasty. The number of wound complications within 21 days will be recorded. As well, the aesthetic appearance and quality of scarring of the scar will be assessed.

NCT ID: NCT06179628 Recruiting - Knee Arthropathy Clinical Trials

Low Versus Standard Concentrations and Volumes Local Anesthetics Boluses for Continuous Adductor Canal Block Under Ultrasound-guidance in Total Knee Arthroplasty

Start date: December 7, 2023
Phase: N/A
Study type: Interventional

Total knee arthroplasty (TKA) is a commonly performed surgical procedure for patients with severe knee osteoarthritis. However, one of the challenges associated with total knee arthroplasty is the significant postoperative pain experienced by patients, which can delay early mobilization and physical therapy. Uncontrolled pain worsens patient outcomes and healthcare costs as it can increase the risk of complications after surgery. Therefore, effective pain management is important for optimizing patient outcomes and promoting a smooth recovery process. The aim of this study is to investigate the efficacy of two different regimens of bupivacaine used in boluses for continuous adductor canal block under ultrasound-guidance in total knee arthroplasty at King Chulalongkorn Memorial Hospital.

NCT ID: NCT06120023 Recruiting - Knee Arthropathy Clinical Trials

Post-Market Clinical Follow Up for Total Knee Arthroplasty System Madison

2022-07
Start date: October 17, 2023
Phase:
Study type: Observational

MADISON Total Knee Prosthesis is intended to be used for total knee arthroplasty to reduce pain and restore joint mobility of the knee. Clinical data for MADISON Total Knee Prosthesis available are not deemed sufficient to support performance and benefits claimed on the whole lifetime of the product. Thus, in order to maintain compliance with the EU regulation (2017/745) related to medical devices and following ISO 14/155:2020, SERF has set up post-market clinical follow-up study (PMCF) to confirm safety and performance of Total Knee Arthroplasty system MADISON. This study is designed to cover the expected 15-years follow-up, to retrieve data according to implant feature (Posterior Stabilized or Ultra Congruent) or fixation method and to gather data related to the revision of partial knee prosthesis. The primary objective of this study is to assess the clinical safety of MADISON total knee prostheses. The secondary objective is to evaluate the survival rates, the clinical performances and clinical benefits of MADISON total knee prosthesis.

NCT ID: NCT06084403 Recruiting - Knee Osteoarthritis Clinical Trials

Ultrasound-Guided Adductor Canal Block for Total Knee Arthroplasty Surgery

Start date: December 20, 2023
Phase: N/A
Study type: Interventional

The ultrasound-guided selective blockade of the saphenous nerve in the adductor canal provides effective analgesia and reduces postoperative pain in patients undergoing arthroscopic medial meniscectomy. Selective blockade of the saphenous nerve in the adductor canal provides effective analgesia without quadriceps muscle weakness. It has been shown that the adductor canal block (ACB) block increases the spread of local anesthetics in a distal and proximal way. Therefore, the proximal spread of local anesthetics may cause possible quadriceps weakness. The distal spread of local anesthetics may increase analgesic effect via sciatic nerve. The different volumes for ACB is a topic of discussion. The aim of this study is to compare the different volumes of US-guided ACB performing for postoperative analgesia management after total knee arthroplasty surgery.

NCT ID: NCT06005623 Recruiting - Knee Arthropathy Clinical Trials

Motivational Feedback Following Total or Unicompartmental Knee Arthroplasty

KneeActivity
Start date: September 15, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized controlled trial (RCT) nested in a prospective cohort study is to investigate whether physical activity (PA) following total knee arthroplasty (TKA) or unicompartmental knee arthroplasty (UKA) can be optimized by the use of an activity tracking device including motivational feedback in comparison with activity tracking without feedback. Furthermore, the project will investigate the predictive value of PA level prior to TKA/UKA for the length of stay, return to work, and quality of life. The main hypothese of the study are: RCT study: - Using an activity tracking device, including motivational feed-back on PA show a superior short-term effect on increased PA (Total counts; primary outcome measure), physical functioning, return to work, and quality of life in comparison with no motivational feed-back from the activity tracker, defined as 'care as usual', in TKA and UKA patients - Using an activity tracking device, including motivational feedback, will have a superior effect on step counts, activity types and pain compared to the standard care, in TKA and UKA patients Prospective cohort: - PA prior to TKA or UKA can work as a predictive measure for function and quality of life following surgery - PA prior to TKA or UKA can work as a predictive measure for the length of hospital stay and return to work Patients will be randomized to activity tracking and motivational feed-back by gamification for patient self-mobilization (Intervention-group) or 'care-as-usual' including activity tracking without motivational feed-back (Control-group). Patients not eligible and/or willing to participate in the RCT study, will be offered to participate in a prospective non-interventional cohort study.

NCT ID: NCT05928403 Recruiting - Knee Arthropathy Clinical Trials

Rate of Return to Sport After Total Knee Prosthesis: Comparison of Three Types of Prostheses

TKA&RTS
Start date: June 11, 2024
Phase:
Study type: Observational

The purpose of the study is the rate of return to sport (regardless of the sport envisaged) after a minimum of 3 years after total knee prosthesis.

NCT ID: NCT05583630 Recruiting - Knee Arthropathy Clinical Trials

Ligament Tension Measurement in Knee Arthroplasty

Start date: October 20, 2022
Phase:
Study type: Observational

1. To develop a new type of knee joint pressure detection device and demonstrate its feasibility 2. To analyze individual differences of knee ligament tension using the new device and explore the influencing factors of ligament tension 3. To explore the correlation between knee ligament tension and postoperative knee function