Kidney Transplant Infection Clinical Trial
Official title:
Study of a Food Supplement (Mannose and Proanthocyanidins Prolonged Release 24h) Versus Proanthocyanidins in the Prevention of Urinary Tract Infections in Kidney Transplant Patients.
The incidence of Urinary tract infections (UTIs) is very high in kidney transplant patients. Most UTIs occur during the first six months (82% within the first three months) of kidney transplantation and are frequently recurrent. The component D-mannose of our authorized food supplement acts by inhibiting the adherence of E.coli to the urothelium. It also has a controlled release formula that ensures the presence in urine of D-mannose and the other components during 24 hours. This is the reason why this experimental study aims to demonstrate that the oral intake of this food supplement is effective in the prevention of UTIs in kidney transplant patients.
The study tries to analyze the impact of a food supplement (Manosar®) on the incidence of urinary infections in patients undergoing kidney transplantation. The patients will be randomly distributed (1: 1 ratio) into two treatment groups of 30 patients each. In one group, they will be treated with Manosar®, and in the other group they will be treated with Proanthocyanidins. All patients will be followed for 6 months, being the first three months of the study drug administration. This experimental study is double-blinded and there are 7 monthly study visits. Properties of D-mannose and Proanthocyanidins make interesting to evaluate the clinical benefit of the use of food supplements with D-mannose and Proanthocyanidins in order to prevent the UTIs without antibiotics. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT02439957 -
A Phase 3 Study of Brincidofovir Versus Valganciclovir for the Prevention of Cytomegalovirus
|
Phase 3 | |
| Not yet recruiting |
NCT06364618 -
Use of Wearables to Detect Infections in Kidney Transplant Recipients
|
||
| Completed |
NCT05142748 -
Study of Pulmonary Infections (Pneumonia) in Kidney Transplant Recipients Admitted to Hospital
|
||
| Terminated |
NCT05747053 -
Personalization of Immunosuppressive Treatment for Organ Transplant Recipients
|
||
| Completed |
NCT03339661 -
Secondary Prophylaxis After CMV Disease in Kidney Transplant Patients Targeted by γδ T Cells Immunomonitoring.
|
Phase 2 | |
| Enrolling by invitation |
NCT05224583 -
Prevalence of BK Viremia in Simultaneous Liver-Kidney Transplant
|
||
| Recruiting |
NCT04701528 -
Anti-Viral Effects of Voclosporin in COVID-19 Positive Kidney Transplant Recipients
|
Phase 2 | |
| Recruiting |
NCT04494776 -
SARS-COV-2 Infection in Kidney Transplant Recipients: a Brazilian Multicenter Study
|
||
| Completed |
NCT02263703 -
Immunogenicity of HPV Vaccine in Immunosuppressed Children
|
Phase 3 | |
| Recruiting |
NCT06219616 -
Prediction of BK Virus Reactivation in Kidney Transplant Recipient
|
N/A | |
| Not yet recruiting |
NCT05708534 -
Evolution of CMV Antiviral T-cell Immunity Over the Next Six Months Initiation of Treatment With Belatacept.
|
||
| Recruiting |
NCT03488771 -
Evaluation of Cell-mediated Immune Response by QuantiFERON Monitor® Assay in Kidney Transplant Recipients
|
||
| Recruiting |
NCT04815954 -
Early vs Late Urinary Catheter Removal After Renal Transplantation
|
N/A | |
| Recruiting |
NCT05727709 -
Dynamic Changes of Torquetenovirus (TTV) Load in Chinese Renal Transplant Recipients
|
||
| Completed |
NCT04542954 -
Optimized Management of Covid-19 Positive Kidney Transplant Recipients: Single Center Experience From the Middle East
|
||
| Active, not recruiting |
NCT03924219 -
CMV T Cell Immunity in Pediatric Solid Organ Transplant Recipients
|
||
| Recruiting |
NCT05836636 -
Immune Monitoring of Prevalent Kidney Transplant Recipients Using Torque Teno Virus: A Single-Center, Prospective Cohort Study
|
||
| Not yet recruiting |
NCT06407232 -
Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients
|
Phase 3 | |
| Completed |
NCT03468478 -
Comparison of the Efficacy and Safety of Sirolimus Versus Everolimus Versus Mycophenolate in Kidney Transplantation
|
Phase 4 | |
| Recruiting |
NCT05397821 -
Pediatric Kidney Transplantation, Ureteroneocystostomy Techniques
|