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Clinical Trial Summary

The BELASWITCH study is a prospective single-centre study including all kidney transplant patients for whom a conversion from Tacrolimus to Belatacept has been decided by the transplant clinicians of the Grenoble Alpes University Hospital. Each patient will be included at the time of conversion (patients stable on Tacrolimus for at least 6 months) and will be their own control 1 year after conversion to Belatacept. The study has two components: - A "Metabolic" benefit arm: the investigators assume that conversion from Tacrolimus to Belatacept reduces the risk of diabetes by reducing the level of insulin resistance. - An "Infectious" risk arm: measurement of the viral load of Torque Teno Virus to assess the state of immunosuppression of patients. In this sense, the investigators hypothesise that it could serve as a biomarker of immunodepression in this population.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05316038
Study type Observational
Source University Hospital, Grenoble
Contact Johan Noble, M.D.
Phone +33 4 76 76 74 73
Email jnoble@chu-grenoble.fr
Status Not yet recruiting
Phase
Start date June 1, 2022
Completion date June 1, 2024

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