Kidney Neoplasm Clinical Trial
Official title:
German National Registry for Nephron-Sparing Surgery
The G-NeSS Registry prospectively collects data on clinical and outcome variables from patients undergoing partial nephrectomy for renal masses. Analyses of data aims at identifying key factors determining the quality of surgical care in this patient population.
Today the majority of patients with renal tumors is diagnosed with localized disease amenable to nephron-sparing surgery (NSS). Partial nephrectomy (PN) constitutes the reference standard treatment for small renal masses according to international guidelines. Open PN ist still the predominant apporach in Germany, but the use of minimally-invasive surgery has continously increased over the last decades. Specifically, robotic surgery is on the rise and may facilitate the adoption of a minimally-invasive PN approach even in more complex renal tumours. Real world data on the outcomes of PN according to the surgical approach are limited. Data from cancer registries and health insurance databases usually lack important information an key patient und tumour characteristics, such as tumour complexity. The G-NESS registry database aims at prospectively collecting such clinical and outcome data from patients undergoing PN. Data collection includes perioperative variables on patient characteristics, tumour location and complexity, surgical approach, intra-/postoperative complications, and kidney function. Follow-up based on questionnaires is conducted after predefined intervals (i.e. 30 days, 12 months, 24 months, and 60 months) in order to receive information on long-term kidney function, comorbidities, and survival. The information received from the database can help to better define the optimal surgical care for patients with renal masses. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Terminated |
NCT01961583 -
[18F]Fluciclatide PET Imaging of Pazopanib Response
|
Phase 2 | |
Completed |
NCT00001302 -
A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833
|
Phase 1 | |
Completed |
NCT01896778 -
Body Warming in Improving Blood Flow and Oxygen Delivery to Tumors in Patients With Cancer
|
N/A | |
Enrolling by invitation |
NCT02287987 -
CLamp vs Off Clamp Kidney During Partial Nephrectomy
|
N/A | |
Recruiting |
NCT04644432 -
Individualized Treatment Strategy for Patients With Metastatic Non-clear Cell Renal Cell Carcinoma
|
Phase 2 | |
Active, not recruiting |
NCT05817604 -
Stereotactic Body Radiotherapy (SBRT) for Medically Inoperable Localised Renal Tumors (SABINA Trial)
|
||
Completed |
NCT00888641 -
A Pilot Study of Renal Hypothermia During Partial Nephrectomy
|
Phase 1 | |
Completed |
NCT00199875 -
Treatment of Patients With Advanced Renal Cancer With a Radiolabeled Antibody, Yttrium-90 Conjugated Chimeric G250
|
Phase 1 | |
Recruiting |
NCT00994188 -
A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members
|
N/A | |
Recruiting |
NCT02346435 -
The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry
|
||
Completed |
NCT01087060 -
Detection of Renal Malignancy of Complicated Renal Cysts
|
N/A | |
Recruiting |
NCT04258462 -
Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors
|
Phase 2 | |
Recruiting |
NCT00898365 -
Study of Kidney Tumors in Younger Patients
|
||
Recruiting |
NCT03996850 -
SPECT/CT for the Characterization of Renal Masses
|
||
Recruiting |
NCT04823923 -
Impact of Chronic Renal Failure on Plasma Exposure of Kinase Inhibitors in Patients Treated for Metastatic Kidney Cancer
|
N/A | |
Not yet recruiting |
NCT05135832 -
Patient Reported Outcomes by Patients With Metastatic Renal Cell Carcinoma
|
N/A | |
Recruiting |
NCT04602702 -
Hyper-Personalized Medicine Using Patient Derived Xenografts (PDXovo) for Metastatic Solid Tumors
|
||
Terminated |
NCT00005655 -
Combination Therapy of Interleukin-12 and Interleukin-2 to Treat Advanced Cancer
|
Phase 1 | |
Recruiting |
NCT05887245 -
Clinical Significance of Adherent Perinephric Fat in Patients Undergoing Partial Nephrectomy
|
||
Recruiting |
NCT06467097 -
Systemic Treatment Alone Versus Systemic Treatment Plus Radiotherapy in Oligometastatic Renal Cell Carcinoma
|
Phase 3 |