Clinical Trials Logo

Clinical Trial Summary

Retrospective studies indicate that active surveillance for clinically localized, small renal masses (cT1a, <=4cm) is safe. It is our hypothesis that active surveillance is safe and efficacious when compared prospectively to patients undergoing immediate intervention for their small renal mass.


Clinical Trial Description

All patients are offered active surveillance or immediate intervention, as applicable, prior to being offered consent for the DISSRM Registry. All patients are enrolled and followed prospectively. Surveillance patients are followed per protocol with serial imaging, blood work and quality of life questionnaires. Intervention patients are followed at the discretion of the attending surgeon with serial QOL appointments/questionnaires. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02346435
Study type Observational [Patient Registry]
Source Johns Hopkins University
Contact Nirmish Singla
Phone 410-502-3692
Email nsingla2@jhmi.edu
Status Recruiting
Phase
Start date January 2009
Completion date January 2024

See also
  Status Clinical Trial Phase
Terminated NCT01961583 - [18F]Fluciclatide PET Imaging of Pazopanib Response Phase 2
Completed NCT00001302 - A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833 Phase 1
Completed NCT01896778 - Body Warming in Improving Blood Flow and Oxygen Delivery to Tumors in Patients With Cancer N/A
Enrolling by invitation NCT02287987 - CLamp vs Off Clamp Kidney During Partial Nephrectomy N/A
Recruiting NCT04644432 - Individualized Treatment Strategy for Patients With Metastatic Non-clear Cell Renal Cell Carcinoma Phase 2
Active, not recruiting NCT05817604 - Stereotactic Body Radiotherapy (SBRT) for Medically Inoperable Localised Renal Tumors (SABINA Trial)
Completed NCT00888641 - A Pilot Study of Renal Hypothermia During Partial Nephrectomy Phase 1
Completed NCT00199875 - Treatment of Patients With Advanced Renal Cancer With a Radiolabeled Antibody, Yttrium-90 Conjugated Chimeric G250 Phase 1
Recruiting NCT00994188 - A Clinical Study of the Living Renal Transplantation With Restored Kidneys Between Family Members N/A
Completed NCT01087060 - Detection of Renal Malignancy of Complicated Renal Cysts N/A
Recruiting NCT04258462 - Hyperpolarized 13C Pyruvate MRI Scan in Predicting Tumor Aggressiveness in Patients With Renal Tumors Phase 2
Recruiting NCT00898365 - Study of Kidney Tumors in Younger Patients
Recruiting NCT03996850 - SPECT/CT for the Characterization of Renal Masses
Recruiting NCT04823923 - Impact of Chronic Renal Failure on Plasma Exposure of Kinase Inhibitors in Patients Treated for Metastatic Kidney Cancer N/A
Not yet recruiting NCT04681690 - German National Registry for NSS
Not yet recruiting NCT05135832 - Patient Reported Outcomes by Patients With Metastatic Renal Cell Carcinoma N/A
Recruiting NCT04602702 - Hyper-Personalized Medicine Using Patient Derived Xenografts (PDXovo) for Metastatic Solid Tumors
Terminated NCT00005655 - Combination Therapy of Interleukin-12 and Interleukin-2 to Treat Advanced Cancer Phase 1
Recruiting NCT05887245 - Clinical Significance of Adherent Perinephric Fat in Patients Undergoing Partial Nephrectomy