Kidney Neoplasm Clinical Trial
Official title:
SPECT/CT for the Characterization of Renal Masses: Impact on Clinical Decision Making
Verified date | July 2023 |
Source | Jonsson Comprehensive Cancer Center |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This trial studies how well technetium Tc-99m sestamibi single-photon emission computed tomography/computed tomography (SPECT/CT) works on clinical decision making in patients with kidney tumors. Diagnostic procedures, such as technetium Tc-99m sestamibi SPECT/CT may be a less invasive way to check for kidney tumors.
Status | Recruiting |
Enrollment | 100 |
Est. completion date | December 31, 2025 |
Est. primary completion date | December 31, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - Performance status Eastern Cooperative Oncology Group (ECOG) < 2. - Life expectancy (> 1 year). - New diagnosis of a renal tumor (within past 3 months). - Measurable, predominantly (> 80%) solid renal neoplasm between 1.5-5.0 cm. - Lesion concerning for kidney cancer bases on a contrast-enhanced CT or magnetic resonance imaging (MRI). - No definitive evidence of metastatic disease. - Does not require urgent surgical treatment. - Candidate for surgical, ablative, and surveillance approach. - Willingness to obtain more information to aid decision-making. - Understanding and willingness to provide consent. Exclusion Criteria: - Presence of multiple solid renal tumors. - A prior needle biopsy of the mass resulting in histologic diagnosis. - A prior diagnosis of kidney cancer. - Presence of an active, untreated, non-renal malignancy. - History of bleeding diathesis or recent bleeding episode. - Prior surgery or radiation therapy to the kidney. - Unwillingness to fill out questionnaires. |
Country | Name | City | State |
---|---|---|---|
United States | UCLA / Jonsson Comprehensive Cancer Center | Los Angeles | California |
Lead Sponsor | Collaborator |
---|---|
Jonsson Comprehensive Cancer Center |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in patient management decision | Assessed with post-test, physician counseling. | 6 months | |
Secondary | Decision making based on tumor size | Could be differentially impacted in two strata, tumors 1.5-3.0 cm and 3.1-5.0 cm. | 6 months |
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