Kidney Failure, Chronic Clinical Trial
Official title:
Glycaemic and Cardiovascular Efficacy of Liraglutide in Prediabetic Patients With End-stage Renal Disease
The present study will examine the effects of liraglutide treatment during 26 weeks on
several cardiovascular risk factors in patients with prediabetes and end-stage renal disease
(ESRD). The primary objective is to determine the efficacy of the treatment on glucose
tolerance evaluated during a 3h 75g-oral glucose tolerance test (OGTT). Secondary objectives
include various clinical and biochemical cardiovascular and safety parameters.
We hypothesise that treatment with liraglutide can improve glucose tolerance in prediabetic
patients with ESRD by normalizing plasma glucose excursions during an OGTT and ameliorate
other cardiovascular risk factors.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment
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