Other Clinical Trial - Dynamic Aspects of Amino Acid Metabolism

Status Recruiting

Clinical Trial Summary

This protocol seeks to define aspects of intestinal and hepatic uptake and metabolism of several amino acids. The major hypothesis to be tested is that the splanchic bed (intestine and liver) conserves essential amino acids and metabolites while synthesizing and metabolizing nonessential amino acids. The aims of the study include defining the relative roles of enteral and hepatic extraction/metabolism in the disposition of glutamate, alanine, methionine and other amino acids. Emphasis will also be placed on studies of the transamination of alpha-ketoisocaproic acid (KIC) to leucine since this reaction is of potential importance in the design of nutritional regimens for patients with renal disease.

Clinical Trial Description

n/a

Study Design

Observational Model: Natural History, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Kidney Diseases

Clinical Trial Details

NCT number	NCT00005767
Study type	Observational
Source	National Center for Research Resources (NCRR)
Contact	Dwight Matthews, Ph.D.
Phone	1-802-646-8114
Status	Recruiting
Phase	N/A

View Details

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