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Keratoconus clinical trials

View clinical trials related to Keratoconus.

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NCT ID: NCT01152541 Active, not recruiting - Keratoconus Clinical Trials

Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic Riboflavin

Start date: June 2010
Phase: Phase 3
Study type: Interventional

Corneal collagen crosslinking (CXL) has been proposed as an effective method of reducing progression of both keratoconus and corneal ectasia after surgery, as well as possibly decreasing the steepness of the cornea in these pathologies. During the CXL procedure, the central corneal thickness has been shown to significantly change. The investigator's believe that better maintenance of corneal thickness potentially could have benefits of better reproducibility of the crosslinking effect with improved predictability of results.

NCT ID: NCT01112072 Active, not recruiting - Keratoconus Clinical Trials

Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia

CXL
Start date: April 2010
Phase: Phase 3
Study type: Interventional

This study will determine the efficacy of corneal collagen crosslinking (CXL) combined with Intacs for the treatment of keratoconus and corneal ectasia. The goal of CXL is to decrease the progression of keratoconus, while Intacs has been shown to decrease corneal steepness in keratoconus. This study will attempt to determine the relative efficacy of the two procedures either performed at the same session versus CXL performed 3 months after Intacs.

NCT ID: NCT00566605 Active, not recruiting - Keratoconus Clinical Trials

Outcomes in a Comparison of Manual Penetrating Keratoplasty and the IntraLase® Enabled Keratoplasty

Start date: August 2007
Phase: Phase 1
Study type: Interventional

To compare the early visual results and postoperative recovery between two groups of keratoconic patients - one group having undergone a traditional, mechanical vacuum trephine procedure while the second group underwent femtosecond-enabled penetrating keratoplasty.

NCT ID: NCT00371202 Active, not recruiting - Keratoconus Clinical Trials

Comparison of Penetrating Keratoplasty and Deep Lamellar Keratoplasty With the Big Bubble Technique for Keratoconus

Start date: July 2006
Phase: Phase 3
Study type: Interventional

it is a randomized clinical trial to compare deep lamellar keratoplasty (DLK) Using big bubble technique and Penetrating Keratoplasty (PK) in patients with keratoconus

NCT ID: NCT00000155 Active, not recruiting - Keratoconus Clinical Trials

The Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study

Start date: June 1995
Phase: N/A
Study type: Observational

To describe the clinical course of keratoconus and to describe the relationships among its visual and physiological manifestations, including high- and low-contrast visual acuity, corneal curvature, slit lamp biomicroscopic findings, corneal scarring, and quality of life. To identify risk factors and protective factors that influence the severity and progression of keratoconus.