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Keratoconjunctivitis clinical trials

View clinical trials related to Keratoconjunctivitis.

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NCT ID: NCT00788229 Completed - Dry Eye Syndromes Clinical Trials

Efficacy and Safety Study of ATs in Patients With Dry Eye Syndrome

Start date: November 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether artificial tears are safe and effective in the treatment of Dry Eye Syndrome.

NCT ID: NCT00717418 Completed - Clinical trials for Keratoconjunctivitis Sicca

Efficacy Study of Cyclosporine Ophthalmic Emulsion in Patients With Dry Eye Disease

Start date: September 2004
Phase: N/A
Study type: Observational

This study will evaluate the efficacy of cyclosporine ophthalmic solution vs. other non-prescription treatments in patients with dry eye disease. Patient and physician assessments completed at baseline, at each follow-up visit (follow-up visits are variable as per physician discretion) and at final follow-up visit.

NCT ID: NCT00681265 Completed - Clinical trials for Keratoconjunctivitis Sicca

Tear Film Break-up Time After Instillation of Artificial Tears

Start date: June 2008
Phase: N/A
Study type: Interventional

This study is an exploratory trial evaluating the tear film break-up time after a single eye drop instillation of over-the-counter artificial tears. The primary hypothesis is that tear film break up time will be greater for test than control eye.

NCT ID: NCT00567918 Completed - Conjunctivitis Clinical Trials

Phase III, Long-Term, Open-Label, Extension Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis

Start date: May 2004
Phase: Phase 3
Study type: Interventional

To investigate the long-term efficacy and safety of FK506 ophthalmic suspension in patients with vernal keratoconjunctivitis

NCT ID: NCT00567762 Completed - Conjunctivitis Clinical Trials

Phase III Study of 0.1% Tacrolimus(FK506) Ophthalmic Suspension in Patients With Vernal Keratoconjunctivitis

Start date: February 2004
Phase: Phase 3
Study type: Interventional

To investigate the efficacy and safety of FK506 ophthalmic suspension on eye symptoms in patients with vernal keratoconjunctivitis

NCT ID: NCT00554879 Completed - Clinical trials for Keratoconjunctivitis Sicca

Acupuncture Treatment of Dry Eye

Start date: November 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the safety and efficacy of acupuncture in the treatment of moderate to severe dry eye by replicating the study design of the previous protocol and to see the study through to its completion.

NCT ID: NCT00445120 Completed - Clinical trials for Vernal Keratoconjunctivitis

Lactobacillus Rhamnosus GG Oral Treatment Efficacy on Vernal Keratoconjunctivitis Treatment

Start date: March 2007
Phase: Phase 2/Phase 3
Study type: Interventional

This interventional study aims to evaluate the efficacy of oral administration of Lactobacillus Rhamnosus GG in preventing relapses of ocular inflammation in Vernal Keratoconjunctivitis (VKC) patients.

NCT ID: NCT00426543 Completed - Fatigue Clinical Trials

Effect of B-cell Depletion in Patients With Primary Sjögren's Syndrome

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The primary purpose of the study is to determine whether B-cell depletion with Rituximab has an effect on the oral, ocular and general disease manifestations in patients with primary Sjögren´s syndrome, that is, an effect on the symptoms of oral and ocular dryness, improvement of the glandular function and a beneficial effect on the general symptoms such as fatigue. The secondary purpose of the study is the investigate the underlying autoimmune and pathophysiological mechanisms in Sjögren´s syndrome.

NCT ID: NCT00426023 Completed - Clinical trials for Vernal Keratoconjunctivitis

Cyclosporin A Eye Drop Treatment in Vernal Keratoconjunctivitis

Start date: February 2007
Phase: Phase 3
Study type: Interventional

This interventional study aims to evaluate the efficacy of Cyclosporine eye drop treatment in preventing relapses of Vernal Keratoconjunctivitis (VKC) and in treating the acute phases of the disease.

NCT ID: NCT00411827 Active, not recruiting - Clinical trials for Keratoconjunctivitis Sicca

Goblet Cell Response and Dry Eye Symptoms After PRK and LASIK

Start date: January 2008
Phase: N/A
Study type: Interventional

Purpose: To develop a screening metric by examining both the characteristics of the preoperative tear film and the intracellular signaling pathways of conjunctival goblet cells in order to determine if there are certain characteristics which might predict those patients who will experience serious dry eye symptoms and complications after refractive surgery. Research Design: This study is a twelve-month prospective non-randomized investigation. Methodology: In conjunction with psychometric questionnaires and various measures of tear film quality (e.g. Schirmer's test, tear break up time, etc), impression cytology will be used to assess the intracellular signaling pathways of conjunctival goblet cells and to determine if alterations in this pathway exist. Alterations in this pathway would result in a reduced response by the mucin secreting conjunctival goblet cells thereby promoting the development of dry eye after refractive surgery.