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Keratoconjunctivitis Sicca clinical trials

View clinical trials related to Keratoconjunctivitis Sicca.

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NCT ID: NCT06435182 Completed - Dry Eye Clinical Trials

Study of OT202 in Treating Moderate to Severe Dry Eye

Start date: April 10, 2023
Phase: Phase 2
Study type: Interventional

This is a phase II study to explore the optimal dosage of OT202 in treating dry eye.

NCT ID: NCT06389214 Completed - Dry Eye Disease Clinical Trials

A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease

Start date: April 9, 2024
Phase: Phase 3
Study type: Interventional

A Randomized, Double-Masked, Vehicle-Controlled Parallel Group Clinical Trial to Assess Efficacy and Safety of 0.25% Reproxalap Ophthalmic Solution Compared to Vehicle in Subjects with Dry Eye Disease

NCT ID: NCT06337981 Completed - Dry Eye Syndromes Clinical Trials

Efficacy and Safety of AJU-S56 in Dry Eye Syndrome Patients

Start date: November 22, 2021
Phase: Phase 2
Study type: Interventional

This study is planned to Evaluate the Efficacy and Safety of test drug (AJU-S56) compared to control drug(vehicle) in Patients with Dry Eye Disease.

NCT ID: NCT06323395 Completed - Dry Eye Disease Clinical Trials

Vizol S Lipid Balance Efficacy and Safety Study in Patients With Dry Eye

Start date: June 1, 2022
Phase: Phase 3
Study type: Interventional

The clinical investigation was intended to investigate the efficacy, ocular tolerability and safety of Vizol S Lipid Balance, a new eye drops, emulsion developed by JADRAN - GALENSKI LABORATORIJ d.d., in patients with moderate to severe evaporative DED after a treatment for 30 days.

NCT ID: NCT06309953 Completed - Dry Eye Clinical Trials

A Study to Evaluate Early Treatment Outcomes With Miebo™ in Subjects With Dry Eye Disease

Start date: February 28, 2024
Phase: Phase 4
Study type: Interventional

An Open-Label, Multicenter, Phase 4 Study to Evaluate Early Treatment Outcomes With Miebo™ in Subjects With Dry Eye Disease

NCT ID: NCT06288945 Completed - Dry Eye Syndrome Clinical Trials

Effect of an Educational Program on Health-related Outcomes of Patients With Dry Eye Syndrome

Start date: January 15, 2023
Phase: N/A
Study type: Interventional

Dry eye syndrome (DES) is a widespread ocular disease affecting the general population. It is a complex disorder affecting the surface of the eye, marked by an imbalance in the tear film and ocular symptoms. Therefore this study was done to determine the effect of an educational program on health-related outcomes of patients with DES including the severity of symptoms related to DES and their influence on visual-related functions

NCT ID: NCT06242860 Completed - Clinical trials for Meibomian Gland Dysfunction

Clinical Study Using Eye Lipid Mobilizer (ELM) With Heat and Vibration To Treat Evaporative Dry Eye Disease

ELM
Start date: February 8, 2022
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to evaluate the Eye Lipid Mobilizer (ELM) for the treatment of evaporative dry eye disease associated with meibomian gland dysfunction. The main questions aim to confirm that 1) the ELM can meet its intended use by validated patient reporting outcomes and 2) to confirm that the ELM device can be used safely by different users within a clinical environment as determined by review of any adverse events related to the use of the device.

NCT ID: NCT06221345 Completed - Cataract Clinical Trials

Hyaluronic Acid-containing Artificial Tears in Post-cataract Surgery Dry Eye Disease

Start date: December 7, 2021
Phase: Phase 4
Study type: Interventional

To compare the effects of hydroxypropyl guar (HPG)/hyaluronic acid (HA)- and carboxymethylcellulose (CMC)/HA-based lubricant eye drops on subjective and objective outcomes in dry eye disease (DED) patients after cataract surgery.

NCT ID: NCT06176651 Completed - Dry Eye Clinical Trials

Evaluation of Miebo (Perfluorohexyloctane) Eyedrops in Habitual Contact Lens Wearers

Start date: September 21, 2023
Phase: Phase 4
Study type: Interventional

Miebo (Perfluorohexyloctane) is a novel, non-aqueous, single entity, preservative free, ophthalmic drop. This drop was recently approved by the Food and Drug Administration (FDA) for the treatment of Meibomian Gland Disease (MGD). All published data on Miebo has been done in non-contact lens wearers. As contact lens dropout rates seem to be an ongoing problem for practitioners, we are performing this study utilizing this novel new drug with contact lens patients to determine if the drops assist comfort in typical soft contact lens wearing patients. If the study determines that Miebo assists in the overall comfort of contact lens patients this could be a possible way to help keep patients in their contact lenses longer.

NCT ID: NCT06159569 Completed - Dry Eye Clinical Trials

Performance and Tolerability of the Medical Device LACRIACT

Start date: September 9, 2021
Phase: N/A
Study type: Interventional

The goal of this study is testing LACRIACT® eye drops, a medical device, to see how well it works and if people can use it safely. The Investigators will study this in people who have dry eyes, some of whom wear contact lenses, and some who do not. To obtain data from 20 participants, the investigators will first screen 22 patients, as two of them may not meet the requirements. If someone quits the study, the Investigators will not replace them with someone else. A person can partecipate in the study if they meet certain criteria in the study plan, complete the entire treatment, and use eye drops correctly at least 80% of the time. The Investigators running the study might also include up to 10 people who wear soft contact lenses out of the 20 in total. This study will be conducted at a clinic in Italy.