Clinical Trials Logo
  1. Home
  2. Joint Diseases
  3. NCT02604446

Depot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty.Tapentadol vs Oxycodone vs Placebo

Joint Diseases Clinical Trial

Official title:
Depot-opioids for Pre- and Postoperative Pain Relief After Primary Knee Arthroplasty. A Double Blinded Randomized Controlled Study. Tapentadol vs Oxycodone vs Placebo

Clinical Trial Summary

This study will provide knowledge about the use of long-acting opioids for pain relief after primary knee arthroplasty. The investigators will compare depot tapentadol, depot oxycodone and placebo for effect on pain relief and side effects. The three study groups reflect the three different postoperative pain regimens that have been used the last years at St. Olavs Hospital, so investigators know that no patient will receive an inadequate pain treatment. The purpose of the study is to find which of the three treatments that gives the best pain relief with the least amount of side effects. The results will be of use for postoperative pain treatment for knee arthroplasty, but also for other types of major surgery. Similar studies that are not sponsored by pharmaceutical industry have not been published yet.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02604446
Study type Interventional
Source St. Olavs Hospital
Contact
Status Completed
Phase Phase 3
Start date September 2015
Completion date February 2019
View Details
See also
  Status Clinical Trial Phase
Withdrawn NCT04976972 - A Comparison of Patients Receiving a Total Knee Replacement With Robotic Assistance or With Conventional Instrumentation N/A
Not yet recruiting NCT03726788 - Intra Articular Injection of Botulinum Toxin Versus Corticoids in Gonarthrosis Phase 2
Completed NCT02944448 - A Study Evaluating Pain Relief and Safety of Orally Administered CR845 in Patients With Osteoarthritis of Hip or Knee Phase 2
Completed NCT02269254 - Persona Versus NexGen N/A
Completed NCT02256098 - RSA RCT: ATTUNE™ TKA Versus PFC Sigma TKA N/A
Completed NCT00815243 - Telemedicine Consultation in Trauma and Orthopedic N/A
Recruiting NCT05564182 - High Intensity Laser Therapy in the Treatment of Hemiplegic Shoulder Pain N/A
Recruiting NCT06142669 - EVOLUTION® Revision STEMMED CS Post Market Clinical Follow-up Study Protocol
Enrolling by invitation NCT04147559 - Post Market Clinical Follow-Up Study for PROFEMUR® Preserve Classic Femoral Stem
Terminated NCT02591368 - MiniTightRope Suspensionplasty Compared With LRTI for the Treatment of Basilar Thumb Arthritis N/A
Completed NCT01227694 - Adult Stem Cell Therapy for Repairing Articular Cartilage in Gonarthrosis Phase 1/Phase 2
Completed NCT00784277 - A Study to Compare the Frequency of Constipation Symptoms With Tapentadol Immediate Release (IR) Treatment Versus Oxycodone IR Treatment in Patients With End-stage Joint Disease Phase 3
Active, not recruiting NCT05618782 - Clinical Trial to Evaluate the Efficacy and Safety of LEVI-04 in Patients With Osteoarthritis of the Knee Phase 2
Recruiting NCT04029792 - Evaluation of a Combination of Plant Extracts (BSL_EP028) on Joint Mobility Phase 1/Phase 2
Active, not recruiting NCT06404346 - Comparative Effectiveness of HVT and Bowen Technique in Patients of SI Joint Dysfunction With Upslipped Innominates N/A
Terminated NCT04712019 - Evaluating Edema and Range of Motion Using Negative Pressure Therapy vs. Standard Surgical Dressing in Bilateral TKA N/A
Completed NCT05650970 - Radial Nerve Mobilization in Hand Thumb Osteoarthritis Patients N/A
Recruiting NCT06074744 - Subsartorial Nerve Block and Femoral Nerve Block in Total Knee Arthroplasty N/A
Completed NCT02315664 - MONITOR-OA: Using Wearable Activity Trackers to Improve Physical Activity in Knee Osteoarthritis N/A
Completed NCT05241691 - Retrospective Evaluation of GGPSP's Safety and Clinical Performance for the Treatment of Lower Limbs Deformities.