Jaundice Clinical Trial
Official title:
Resting State Functional Magnetic Resonance Imaging Study of Jaundice Infants Before and After Light Treatment.
It is just an observation study. The investigates want to explore the signal changes of
resting state functional Magnetic resonance Imaging (fMRI) after light treatment in jaundice
infants. Signal changes contain blood oxygenation level dependent (BOLD) and arterial spin
labeling (ASL).Indicator of BOLD is amplitude of low-frequency fluctuation（ALFF).Indicator
of ASL is cerebral blood flow (CBF).
The investigates assume that the children with jaundice after light therapy, ALFF and CBF
will change. Focus on the globus pallidus and subthalamic nuclei. The two brain regions were
proved to be abnormal in MRI T1, T2 structure signal in kernicterus.
Doctors observe the status of infants aside.Using monitoring probe can see clearly.
resting state fMRI scan light therapy the second time resting state fMRI scan ;
Observational Model: Case-Crossover, Time Perspective: Prospective
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