Jaundice, Neonatal Clinical Trial
Official title:
Role of Probiotics Administered as an Adjuvant Therapy in Pathological Neonatal Unconjugated Hyperbilirubinemia
Hyperbilirubinemia is a prevalent problem in babies that necessitates medical attention. Probiotic administration as adjuvant therapy may have a positive impact on the pathological neonatal unconjugated hyperbilirubinemia.
Neonatal jaundice is a common health care issue that affects approximately 9% of newborns after birth. The percent of neonates who acquire jaundice in the first week of their birth is about 60%. while the percent of breasted neonates who develop jaundice during the first month of their birth is about 10%. Phototherapy is the standard therapy for neonates who develop pathological jaundice, as it can alter bilirubin structure and increase its excretion. Probiotics can also be used for the treatment of jaundice. The efficacy of probiotics depends on their ability to pass across the GIT and cause colonization in the intestinal lumen. Hence, it leads to a decrease in the bacterial growth in the small bowel, a reduction in the function of the gastrointestinal barrier, and a regulation of the immune system of the host. ;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT00735319 -
Transcutaneous Bilirubinometers in the Community
|
N/A | |
Completed |
NCT00114543 -
Trial of Aggressive Versus Conservative Phototherapy in Infants <1,000 Grams Birth Weight
|
Phase 3 | |
Withdrawn |
NCT04021927 -
Development of a Neonatal Jaundice Treatment Accelerator by Redirection of Unused Light During Phototherapy
|
N/A | |
Completed |
NCT01887327 -
Stannsoporfin With Light Therapy for Newborn Babies With Jaundice
|
Phase 2 | |
Completed |
NCT04632888 -
The Effect of Telephone Support for Breastfeeding Follow-up on Infantile Colic and Maternal Breastfeeding Self-efficacy
|
N/A | |
Not yet recruiting |
NCT04527536 -
Research of Diagnostic Value for BMJ Infants
|
||
Suspended |
NCT03741803 -
Relationship Between Delayed Cord Clamping at Birth and Neonatal Bilirubin Levels in Parturients With a Prior Child Requiring Therapy for Neonatal Jaundice
|
N/A | |
Completed |
NCT05650463 -
Evaluation of a Smartphone-based Screening Tool (Picterus Jaundice Pro) for Neonatal Jaundice in Dark Skin Newborns
|
N/A | |
Terminated |
NCT05623566 -
Evaluation of a Smartphone Based Screening Tool for Neonatal Jaundice in Surabaya, Indonesia
|
N/A | |
Completed |
NCT02612727 -
Filtered Sunlight Phototherapy to Treat Significant Jaundice: Safety and Efficacy in Neonates
|
N/A | |
Completed |
NCT01434810 -
Treatment of Neonatal Jaundice With Filtered Sunlight Phototherapy: Safety and Efficacy in African Neonates
|
N/A | |
Completed |
NCT03184948 -
Understanding Neonatal Jaundice in Rwanda
|
N/A | |
Completed |
NCT03942757 -
BiLirubin Decrease Under Phototherapy Exposure in the Preterm Newborn in Incubator
|
||
Not yet recruiting |
NCT05806684 -
Hyperbilirubinemia and Retinopathy of Prematurity in Preterm Infants: a Retrospective Study.
|
||
Completed |
NCT06372093 -
Evaluation of Bilirubin Measurements in Newborns From Smartphone Digital Images in a Population in Botswana
|
N/A | |
Completed |
NCT03569254 -
Effectiveness, Safety and Perceptions With the Use of One LED Blanket Device in the Ambulatory Treatment of Jaundice
|
N/A | |
Completed |
NCT03570775 -
Effectiveness, Safety and Perceptions With the Use of One LED Sleeping Bag Device in the Treatment of Neonatal Jaundice
|
N/A | |
Completed |
NCT05625880 -
Evaluation of Bilirubin Estimates in Newborns From Smartphone Digital Images in a Nepali Population
|
N/A | |
Completed |
NCT01169740 -
Transcutaneous Measurement of Jaundice in the Newborn
|
N/A | |
Completed |
NCT05623553 -
Evaluation of a Smartphone Based Diagnostic Tool to Assess Neonatal Jaundice in a Mexican Population
|
N/A |