Clinical Trials Logo

Clinical Trial Summary

The purpose of this study is to provide patients who have received at least one islet transplant as a previous participant in a Clinical Islet Transplantation Consortium (CIT) clinical trial with maintenance immunosuppressive medications and to collect information about the safety of the medications and islet function.


Clinical Trial Description

After islet-cell transplantation in the CIT studies*, each subject receives maintenance immunosuppressive medications.

The purpose of this protocol is to collect additional follow-up for safety and efficacy from CIT subjects with graft function after their completion in their CIT parent study. It is expected that most subjects will retain measurable islet function and, in the islet-alone studies, continue to receive immunosuppressive medications at the time of completing their CIT parent study.

*CIT parent studies: CIT02 (NCT00464555), CIT03 (NCT00434850), CIT04 (NCT00468403), CIT05 (NCT00468442), CIT06 (NCT00468117), and CIT07 (NCT00434811) ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01369082
Study type Observational
Source National Institute of Allergy and Infectious Diseases (NIAID)
Contact
Status Completed
Phase N/A
Start date May 2011
Completion date July 2017

See also
  Status Clinical Trial Phase
Withdrawn NCT01123122 - A Comparison of Strict Glucose Control With Usual Care at the Time of Islet Cell Transplantation N/A
Completed NCT00417131 - Imaging of Islet Transplantation With PET and MRT N/A
Not yet recruiting NCT05973734 - Islet Transplantation With Recipient T-Reg Cells or Deceased Donor Vertebral Bone Marrow Therapy Phase 1
Completed NCT02627690 - Nephrologic Prognosis 10 Years After Diabetes Cell Therapy
Terminated NCT00853944 - Effect of Sitagliptin on Graft Function Following Islet Transplantation Phase 3
Completed NCT03427931 - CGM Use in Islet Transplant Recipients N/A
Terminated NCT00409461 - Comparison of Sirolimus Alone With Sirolimus Plus Tacrolimus in Type 1 Diabetic Recipients of Cultured Islet Cell Grafts N/A