Clinical Trials Logo
  1. Home
  2. Ischemia
  3. NCT02648230

PrEssure wiRe Compared to Microcatheter-based Sensing Technology For the Evaluation of FFR Measurements — PERFORM  

Ischemia Clinical Trial

Official title:
PrEssure wiRe Compared to Microcatheter-based Sensing Technology For the Evaluation of cORonary Fractional Flow Reserve Measurements

Clinical Trial Summary

The model by which physicians measure the lack of blood flow in the vessels that supply blood to the heart muscle is called Fractional Flow Reserve (FFR). FFR is the measurement of the pressure across the vessels that supply blood to the heart. These are known as the coronary arteries. This study involves comparing two FFR wires, the St. Jude Medical Pressure Wire (PW) and the ACIST Navvus Microcatheter (MC) to check the accuracy of the devices. FFR allows real-time estimation of the effects of a narrowed vessel, whereas standard angiography can underestimate or overestimate narrowing, because it only visualizes contrast (the different areas of color) inside a vessel.

Clinical Trial Description

Fractional flow reserve (FFR) measurement by pressure wire (PW) under hyperemic conditions has become the invasive gold standard for determining the physiologic extent of cardiac ischemia, and which has been validated in several clinical outcomes studies as a way of optimizing case selection for percutaneous coronary intervention (PCI). More recently a microcatheter (MC)-based sensor measurement of fractional flow reserve has been introduced. Small scale in-vivo comparisons have been performed suggesting the utility of this approach to measure FFR,but these data are limited and have not been independently validated. This non-randomized, prospective study is designed to evaluate the accuracy of MC-based FFR measurement to the PW standard in lesions subjected to FFR assessment in routine clinical practice. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02648230
Study type Interventional
Source Columbia University
Contact
Status Completed
Phase N/A
Start date December 2015
Completion date December 8, 2016
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05443061 - Subcutaneous Nitroglycerin to Prevent Radial Artery Occlusion in Children N/A
Recruiting NCT05158257 - Clinical Of Plain Balloon Dilatation Combined Stent Versus Endovascular Debulking Combined Drug-coated Balloon to Treat Arteriosclerosis Occlusive Disease of Lower Extremity N/A
Recruiting NCT06006975 - Early Warning of Delayed Cerebral Ischemia
Completed NCT02758847 - Evaluation of Paclitaxel in Patients With CLI and Femoropopliteal Occlusive Disease Treated With DCB Angioplasty N/A
Not yet recruiting NCT02871622 - BMX Alpha Registry: a Post-market Registry of the BioMatrix Alpha TM N/A
Completed NCT02557282 - CARESTREAM Vue PACS v12.1.5 CT Perfusion Clinical Protocol
Enrolling by invitation NCT02033681 - Optimal Time Delay of Epinephrine Injection With "One-per-mil" Tumescent Solution N/A
Completed NCT01608035 - Sciatic Perineural Versus Stump Catheter for Below Knee Amputation Phase 0
Active, not recruiting NCT01518842 - Effect of Intravitreal Bone Marrow Stem Cells on Ischemic Retinopathy N/A
Completed NCT01625832 - Effects of Coronary Sinus Occlusion on Myocardial Ischemia (Pilot Study) N/A
Active, not recruiting NCT01281241 - Study on Mechanical and Electrical Alternans N/A
Completed NCT00778323 - Clinical Trial of Remote Preconditioning in Patients Undergoing Cervical Decompression Surgery Phase 1/Phase 2
Completed NCT00371371 - Intra-arterial Stem Cell Therapy for Patients With Chronic Limb Ischemia (CLI) Phase 1/Phase 2
Terminated NCT00760708 - Circulating Adenosine Levels Before and After Intravenous (IV) Persantine
Not yet recruiting NCT06039748 - Angiography-Derived Quantitative Functional Assessment Versus Pressure-Derived FFR and IMR: The FAIR Study
Completed NCT04879875 - New Method for Real-time Detection of Tissue Ischemia (ISCALERT) N/A
Completed NCT00526474 - Trial to Assess the Effects of Vorapaxar (SCH 530348; MK-5348) in Preventing Heart Attack and Stroke in Patients With Atherosclerosis (TRA 2°P - TIMI 50) (P04737) Phase 3
Completed NCT03994822 - pRESET for Occlusive Stroke Treatment N/A
Completed NCT02910778 - The Effect of Ticagrelor With or Without Atorvastatin on Endothelial Function in Healthy Males Phase 4
Completed NCT02703142 - Endoscopic Evaluation After Esophagectomy N/A