Ischemia Clinical Trial
Official title:
Inspired Helium for Ischemic Protection During Knee Replacement Surgery
The purpose of this study is to determine whether breathing in helium reduces indications of
injury to the skeletal muscle seen in blood tests after knee replacement surgery.
The ability to reduce the risk of skeletal muscle injury may help improve patient safety by
providing protection to the area of the body having its blood supply interrupted during a
particular surgery.
During hospitalization, beginning the day after surgery, additional tests will be added to
the daily standard of care blood samples. When daily blood samples are not ordered as part of
a study participants care after surgery, blood samples only for the study tests, may be done.
Up to 60 study participants will be selected to be in one of two possible groups.
After hospital discharge the study participants physical therapist will be contacted for
copies of the notes and reports about the participants progress in physical therapy. This
information will be used to evaluate if the different breathing gases have any impact on how
quickly people recover after surgery.
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