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Study of Autologous Bone Marrow Concentrate for the Treatment of Critical Limb Ischemia (CLI)

Ischemia Clinical Trial

Official title:
Feasibility Study of the Safety and Activity of Autologous Bone Marrow Aspirate Concentrate (BMAC) for the Treatment of Critical Limb Ischemia Due to Peripheral Arterial Occlusive Disease

Clinical Trial Summary

Injections of concentrated bone marrow mononuclear cells into ischemic tissues will result in vasculogenesis

Clinical Trial Description

Bone marrow aspirate is collected and processed by centrifugation to remove red blood cells. The buffy coat is concentrated by removing plasma. The resultant concentrate of cells is injected into ischemic tissues of the lower limb. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00498069
Study type Interventional
Source Harvest Technologies
Contact
Status Completed
Phase N/A
Start date November 2007
Completion date March 2015
View Details
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