Feasibility Assessment of Cardiovascular Endurance Training for

Status Recruiting

Clinical Trial Summary

This exploratory study's primary objective is the changes of irritable bowel syndrome (IBS) symptom severity by cardiovascular endurance training (CET) in relation to the baseline sedentary or non-active lifestyle. Secondary endpoints focus on the mechanisms associated with these changes. These mechanisms relate to dietary adaptations, changes in anxiety, depressive comorbidity, somatisation, alterations in the gut microbiome or metabolome, body composition and measures of cardiovascular fitness. Virtually all IBS guidelines mention lifestyle modifications as a management option. Research on the role of physical activity remains underassessed as compared to the other interventions. Therefore, an exploratory proof-of-concept study will investigate the influence of regular physical exercise on symptoms in a small group of IBS patients. This study will gather data on putative underlying mechanisms related to dietary factors, faecal microbiome and metabolome, mental well-being, body composition and cardiovascular fitness.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05680766
Study type	Interventional
Source	Universitair Ziekenhuis Brussel
Contact	Sébastien Kindt
Phone	+32 2 477
Email	sebastien.kindt@uzbrussel.be
Status	Recruiting
Phase	N/A
Start date	October 16, 2023
Completion date	January 2, 2027

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Feasibility Assessment of Cardiovascular Endurance Training for the Symptomatic Improvement of Irritable Bowel Syndrome Patients With a Sedentary and Non-active Lifestyle.

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms