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Clinical Trial Summary

To assess the effects of a Human Milk Oligosaccharide mix given once daily for 12 weeks on stool consistency and abdominal pain compared to placebo in individuals with Irritable Bowel Syndrome (IBS).

Clinical Trial Description

HMO mix has been shown to provide therapeutic benefits to individuals with IBS of all subtypes (Palsson et al., 2019). DSM is planning this trial in order to investigate if clinically relevant improvements in bowel movements and IBS symptoms can be obtained through the use of the HMO mix in individuals with moderate to severe IBS and abdominal pain. Eligible participants will have a diagnosis of Irritable Bowel Syndrome (IBS). Participants will be assessed for eligibility at the screening visit, must meet all the inclusion criteria, and none of the exclusion criteria. In this trial, participants will be randomized to one of two intervention groups (a Human Milk Oligosaccharide mix or placebo) and receive intervention for at least 12 weeks. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05205785
Study type Interventional
Source DSM Nutritional Products, Inc.
Contact Aisling Harrington
Phone +353 21 430 7442
Status Recruiting
Phase N/A
Start date March 22, 2023
Completion date January 2025

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