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NCT04512898 Clinical Trial

Helicobacter Pylori Eradication and Irritable Bowel Syndrome: A Prospective Study

Irritable Bowel Syndrome Clinical Trial

Official title:
Effect of Helicobacter Pylori Eradication on Symptoms and Quality of Life of Irritable Bowel Syndrome: A Prospective Study

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT04512898
Other study ID # H. Pylori
Secondary ID
Status Not yet recruiting
Phase Phase 4
First received
Last updated
Start date August 10, 2020
Est. completion date November 10, 2020

Study information
Verified date August 2020
Source Assiut University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

H. Pylori is frequently observed in patients with irritable bowel syndrome(IBS). However, the effect of H. pylori eradication on IBS is not clear.

Description:

Patients with IBS symptoms using Rome IV criteria will be included. Testing for H. pylori will be done. Patients with H. pylori will receive triple therapy and followed after two weeks for eradication and assessment of IBS symptoms.

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 100
Est. completion date November 10, 2020
Est. primary completion date November 10, 2020
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria:

- Patients newly diagnosed with IBS and H.pylori

Exclusion Criteria:

- Patients received previous treatment of H.pylori

- Patients receiving treatment for IBS.

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Triple therapy for H.pylori
Triple therapy of proton pump inhibitors, clarithromycin and metronidazole.

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Assiut University

Outcome
Type Measure Description Time frame Safety issue
Primary Questionnaire for Rome IV criteria Symptoms of IBS 2 weeks
Secondary Quality of life questionnaire Quality of life. 2 weeks
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