Fecal Microbiota Transplantation for Irritable Bowel Syndrome

Status Recruiting

Clinical Trial Summary

Fecal microbiota transplantation (FMT) is a strategy that infuses a fecal suspension containing a healthy donor's microbiota into a patient's gut to restore his/her intestinal microbiome. FMT has a higher cure rate than standard antibiotic treatment for recurrent Clostridium difficile infections,and shows promising results in Inflammatory bowel disease（IBD）.However, few studies have evaluated whether FMT is effective to treat Irritable bowel syndrome(IBS).The investigators propose to determine the efficiency and safety of FMT in patients with Irritable bowel syndrome.

Clinical Trial Description

The present clinical trial aims to re-establish a gut functionality state of intestinal flora through FMT as a therapy for Irritable bowel syndrome(IBS). We established a standard microbiota isolation from donated fresh stool in lab. Then the microbiota is transplanted to the whole colon through a tube. Patients from Guangzhou First People's Hospital in this study will be assigned to receive FMT at least two times according to associated guidelines and follow-up for at least six months. Questionnaires will be used to assess participants at study start and at study completion. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03613545
Study type	Interventional
Source	Guangzhou First People's Hospital
Contact	Hongli Huang, MM
Phone	86-13631316718
Email	honglisums@126.com
Status	Recruiting
Phase	Phase 2/Phase 3
Start date	August 10, 2018
Completion date	December 31, 2030

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