Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome

Irritable Bowel Syndrome Clinical Trial

Official title:

Brain Imaging, Heart Rate Variability and Serum Fatty Acid in Subjects With Irritable Bowel Syndrome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02179905
• Other study ID #: SKH-8302-102-DR-14
• Status: Completed
• Phase: N/A
• First received: June 4, 2014
• Last updated: July 1, 2014
• Start date: January 2013
• Est. completion date: September 2013

Study information

• Verified date: June 2014
• Source: Shin Kong Wu Ho-Su Memorial Hospital
• Contact: n/a
• Is FDA regulated: No
• Health authority: Taiwan: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

This study is to analyze the relationship between brain structure, the heart rate variability and the serum fatty acid component of the irritable bowel syndrome patients.

Description:

Several studies showed that the gray matter and white matter of the brain related to the symptoms of irritable bowel syndrome patients.

The investigators study is to analyse the relationship between thickness of cortex of irritable patients, the sympathetic tone and the serum fatty acid component of the irritable bowel syndrome patients. It is to clarify the mechanism of irritable bowel syndrome, whether the symptoms of irritable bowel syndrome are related to the thickness of cortex or inflammation status of the body.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 69
• Est. completion date: September 2013
• Est. primary completion date: September 2013
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 20 Years to 50 Years

Eligibility

Inclusion Criteria:

• female

• between 20 and 50 years old

• meet Rome III criteria

Exclusion Criteria:

• colon and small intestinal disease

• psychiatric disease patients

• patients received major surgery in the past 5 years

• diabetic patients

• patients with metal implant

Study Design

Observational Model: Case Control

Related Conditions & MeSH terms

• Irritable Bowel Syndrome
• Syndrome

Locations

Country	Name	City	State
Taiwan	Shin Kong Wu Ho-Su Memorial Hospital	Taipei

Sponsors (1)

Lead Sponsor	Collaborator
Shin Kong Wu Ho-Su Memorial Hospital

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	The relationship between heart rate variability and symptoms of irritable bowel syndrome patients.		Patients who suffered from IBS for more than 5 years.	No
Other	The relationship between component of fatty acid and symptoms of irritable bowel syndrome patients.		Patients who suffered from IBS for more than 5 years.	No
Primary	The relationship between brain structure, heart rate variability and fatty acid of the irritable bowel syndrome patients.		Patients who suffered from IBS for more than 5 years.	No
Secondary	The relationship between thickness of brain cortex and the symptoms of irritable bowel syndrome		Patients who suffered from IBS for more than 5 years.	No