A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome

Irritable Bowel Syndrome Clinical Trial

Official title: A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome

Status Completed

Clinical Trial Summary

This study is being done to see if St. John's wort helps people with irritable bowel syndrome, otherwise known as "IBS". St. John's wort is a herbal supplement derived from the St. John's wort plant. It has been shown to be helpful in several medical conditions such as depression as well as other pain syndromes.

Clinical Trial Description

Eligibility criteria:

1. Established diagnosis of IBS

2. 18-70 years of age

4) U.S. resident 5) English-speaking (able to provide consent and complete questionnaires) 6) Able to participate in all aspects of the study

You will be asked to do the following:

• Undergo a screening interview and physical examination

• Take a urine pregnancy test (if applicable)

• Take a study pill twice daily for 12 weeks(3 months)

• Complete daily symptom diaries and bi-weekly questionnaires for 12 weeks.

• Complete a questionnaire at 6 months after the active phase of the study is over. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Irritable Bowel Syndrome
• Syndrome

• NCT number: NCT00587860
• Study type: Interventional
• Source: Mayo Clinic
• Status: Completed
• Phase: Phase 2
• Start date: February 2006
• Completion date: March 2008