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Irritable Bowel Syndrome clinical trials

View clinical trials related to Irritable Bowel Syndrome.

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NCT ID: NCT04276961 Recruiting - Clinical trials for Irritable Bowel Syndrome

Efficacy of Acupuncture in Refractory Irritable Bowel Syndrome

Start date: October 15, 2020
Phase: N/A
Study type: Interventional

The trial aims to examine the efficacy and safety of acupuncture in the treatment of refractory irritable bowel syndrome (IBS). The investigators will include 170 participants to receive acupuncture plus usual care or sham acupuncture plus usual care. Twelve sessions of acupuncture will be delivered to participants over a period of 4 weeks. The primary outcome is defined as proportion of participants with adequate relief of global IBS symptoms at week 8, which is defined as >50% reduction in IBS-SSS scale.

NCT ID: NCT04270487 Completed - Clinical trials for Irritable Bowel Syndrome

The DOMINO Trial: Diet Or Medication in Irritable Bowel syNdrOme

DOMINO
Start date: July 26, 2018
Phase: Phase 4
Study type: Interventional

A randomized controlled trial to evaluate the short-term efficacy and long-term health economic impact of a dietary intervention compared to pharmacotherapy with a musculotropic spasmolytic agent for newly diagnosed or newly treated irritable bowel syndrome in primary care.

NCT ID: NCT04256551 Completed - Clinical trials for IBS - Irritable Bowel Syndrome

Effects of a Novel Machine Learning Mobile App on Diet Adherence in Individuals Following the Low Fodmap Diet

Start date: January 23, 2020
Phase: N/A
Study type: Interventional

A high fermented, oligio-, di-, monosaccharide, and polyols (FODMAP) diet has been shown to exacerbate the symptoms of irritable bowel syndrome (IBS). Previous literature has shown significant improvement in IBS symptoms after adherence to a low FODMAP diet (LFD); hence, LFD is a viable treatment method for IBS and IBS-like symptoms. However, adherence to the LFD has proven to be difficult with participants stating that information provided by medical practitioners is generalized and nonspecific requiring them to search for supplementary information to fit their individual needs. Notably, studies that have used a combination of online and in-person methods for treatment have shown improved adherence to the LFD. The purpose of this study is to determine whether a novel machine learning dietary mobile application (ML-App) will improve adherence to the LFD compared to a standard online dietary intervention in populations with IBS or IBS-like symptoms over a 4 week period.

NCT ID: NCT04247100 Terminated - Clinical trials for Irritable Bowel Syndrome

A Study of Randomized Sham-control Auricular TENS Unit Stimulation in Pediatric Functional Gastrointestinal Disorders

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to see if using a micro-current through a device called a TENS (Transcutaneous Electrical Nerve Stimulator) unit helps to improve functional gastrointestinal disorder (FGID) symptoms in children by stimulation of the vagus nerve. The study will compare two methods of stimulation to determine if there is a difference in the two methods.

NCT ID: NCT04245254 Completed - Clinical trials for Irritable Bowel Syndrome

GutMe!: IBS and Collagen Protein Powder an Interventional Study

GutMe
Start date: May 15, 2020
Phase: N/A
Study type: Interventional

In this study we would like to understand how or if a food-based supplement affects gut symptoms such as bloating, stomach cramps and irregular bowel habits. Through using a digital symptom tracking app for a few weeks, you may just learn more about exactly what is triggering your symptoms!

NCT ID: NCT04236843 Completed - Clinical trials for Irritable Bowel Syndrome

Faecal Microbiota Transplantation (FMT) in Patients With IBSmechanism(s) of Action

Start date: February 3, 2020
Phase: N/A
Study type: Interventional

Two hundrad patients are randomized to either 90 g transplant, 90 g transplant twice with 1week interval into the distal small intestine via working channel of a gastroscope, or to 90 g transplant into the coecum of the colon via working channel of a colonoscope. The patients shall complete 5 questionnaires measuring symptoms, fatigue and quality of life and collect a feces sample at the baseline, and at 3, 6 and 12 months after FMT. Dysbiosis and fecal bacterial are determined by using 16S rRNA gene.

NCT ID: NCT04231279 Terminated - Clinical trials for Irritable Bowel Syndrome

Recurrent Abdominal Pain and Exocrine Pancreatic Insufficiency

Start date: January 28, 2022
Phase: Phase 3
Study type: Interventional

This is a 3-year prospective study too identify the role of exocrine pancreatic insufficiency in patients with abdominal pain who are undergoing upper endoscopy. An endoscopic pancreatic function test (ePFT) with secretin will be performed in children undergoing routine investigative EGD. The goal of this study is to identify the role of exocrine pancreatic insufficiency in patients with abdominal pain who are undergoing upper endoscopy, who otherwise would be labelled as recurrent abdominal pain (RAP).

NCT ID: NCT04225104 Completed - Clinical trials for IBS - Irritable Bowel Syndrome

Yogic Breathing and IBS

Start date: April 15, 2019
Phase: N/A
Study type: Interventional

Adults with irritable bowel syndrome (IBS) are being randomized to a yogic breathing or control condition. Participants randomized to the yogic breathing group will be asked to complete a 2-minute yogic breathing video 5 to 7 days per week at home for 4 weeks and control group participants will be asked to maintain their current activities. Participants in this group will be given access to the yogic breathing video at the end of the 4-week control period. IBS symptoms and autonomic and vascular function will be assessed at baseline and at the end of week 4 in both groups.

NCT ID: NCT04217733 Recruiting - Clinical trials for IBS - Irritable Bowel Syndrome

Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome

Start date: November 1, 2019
Phase: Phase 3
Study type: Interventional

Ethosuximide and pentoxifylline in the treatment of abdominal pain related to irritable bowel syndrome

NCT ID: NCT04214470 Recruiting - Clinical trials for Irritable Bowel Syndrome

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBS

Start date: March 2, 2020
Phase:
Study type: Observational

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.