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Irritable Bowel Syndrome clinical trials

View clinical trials related to Irritable Bowel Syndrome.

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NCT ID: NCT06456710 Completed - Clinical trials for Irritable Bowel Syndrome

Effect of a Psychological Intervention on Stigma: a Randomized Controlled Study

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

The purpose of this study was to construct a Stigma intervention program for college students with Irritable Bowel Syndrome (IBS) based on the Acceptance and Commitment Therapy (ACT) theory and to investigate the effectiveness in reducing stigma in IBS patients with the aim of enhancing their mental health and improving their quality of life.

NCT ID: NCT06426745 Completed - Colonic Polyp Clinical Trials

Split-dose Versus Single-dose Bowel Preparation for Colonoscopy

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Colonoscopy is the current standard method for evaluation of colonic disorders such as colorectal cancer, IBD, polyps, and other conditions.

NCT ID: NCT06423586 Completed - Clinical trials for Irritable Bowel Syndrome

Effect of Lecithin-based Curcuma and Boswellia on Post-acute COVID-19 IBS

Start date: September 1, 2021
Phase: N/A
Study type: Interventional

This open-label study investigates the effects of lecithin-based formulations of Curcuma longa (Meriva™) and Boswellia serrata (Casperome™) extracts on post-acute COVID-19 irritable bowel syndrome (PCIBS) and irritable bowel syndrome (IBS) without prior COVID-19 infection. A total of 44 participants, 16 with PCIBS and 28 controls with IBS, were supplemented for 30 days. Outcomes measured included abdominal bloating, abdominal pain, enteral dysbiosis, and global assessment of efficacy. The study found significant reductions in bloating and pain in both groups, with a notable decrease in dysbiosis only in the IBS group. This suggests potential benefits of the supplementation in managing gastrointestinal symptoms associated with PCIBS and IBS.

NCT ID: NCT06421922 Completed - Clinical trials for Irritable Bowel Syndrome-IBS

Effect of Different Dietary Therapies on Intestinal Barrier Integrity in Patients With Irritable Bowel Syndrome

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

This study aims to evaluate the effects of different dietary treatments on intestinal integrity in female subjects aged 19-50 years previously diagnosed with constipation-predominant irritable bowel syndrome (IBS). At the Gülhane Training and Research Hospital's gastroenterology clinic in Ankara, Turkey, a randomized controlled experiment was carried out. 60 individuals with IBS were randomly divided into three groups. Group 1 was assigned to a regular constipation diet, group 2 to a constipation diet rich in soluble fibers, and group 3 to a constipation diet with probiotic yogurt supplementation. Every individual was monitored for eight weeks. Plasma zonulin level was used to measure intestinal integrity both before and after treatment.

NCT ID: NCT06407609 Completed - Clinical trials for Irritable Bowel Syndrome

Positive Outcomes of the Supplementation With Lecithin-based Delivery Form of Curcuma Longa and of Boswellia Serrata in IBS

Start date: September 3, 2022
Phase: N/A
Study type: Interventional

Small bowel dysbiosis (SBD), is a frequent finding in subjects with irritable bowel syndrome (IBS). The formula-tion in sunflower lecithin (Phytosome) of Curcuma longa and Boswellia serrata demonstrated beneficial effects on intestinal microbiota. The aim of this study was to evaluate the effect of a lecithin-based delivery formulation of Curcuma longa and of Boswellia serrata extracts (CUBO), on SBD in IBS subjects.

NCT ID: NCT06187298 Completed - Clinical trials for Irritable Bowel Syndrome

Effect of Oral Combined Berberine and Curcumin Pharmacological Therapy on IBS

Start date: August 25, 2020
Phase:
Study type: Observational

Irritable bowel syndrome (IBS) is a prevalent, chronic functional gastrointestinal (GI) disorder, characterized by recurrent abdominal discomfort (pain) associated with altered bowel movements. IBS has a considerable negative impact on people's quality of life (QoL). There is currently no specific treatment available for IBS; most of the therapeutic management is symptomatic. Reported evidence suggest that BBR and CUR can alleviate symptoms of IBS through their multiple pharmacological effects including preventing stress-induced intestinal inflammation and visceral hypersensitivity, reducing bowel motility, and regulating intestinal permeability, gut microme and gut-brain axis.

NCT ID: NCT06167018 Completed - Clinical trials for Irritable Bowel Syndrome

Nurse-administered, Gut-directed Hypnotherapy for Patients With Irritable Bowel Syndrome (IBS).

Start date: September 2005
Phase:
Study type: Observational

Adult IBS patients with symptoms refractory to standard medical treatment received nurse-administered, gut-directed hypnotherapy. The primary outcome measure was change in gastro-intestinal symptom severity.

NCT ID: NCT06028035 Completed - Clinical trials for Irritable Bowel Syndrome-bile Acid Diarrhea

A Study of Hemp Hull WFI for IBS Diarrhea

Start date: October 6, 2023
Phase: N/A
Study type: Interventional

The purpose of this study is the effect of a study bar, which contains 15 grams of insoluble dietary fiber total sourced from Hemp hulls, on intestinal permeability in irritable bowel syndrome (IBS)-bile acid diarrhea individuals.

NCT ID: NCT05978973 Completed - Clinical trials for Irritable Bowel Syndrome

Elemental Diet and Gut Microbiome

Start date: August 6, 2023
Phase: N/A
Study type: Interventional

he primary objective of this study is to assess changes in stool microbiome profiles in patients after an elemental diet.

NCT ID: NCT05947929 Completed - Clinical trials for Irritable Bowel Syndrome

Aerobic Exercise Verus Acupuncture on the Quality of Life in Women Suffering From Irritable Bowel Syndrome

Start date: May 20, 2021
Phase: N/A
Study type: Interventional

To compare the effect of aerobic exercise and the acupuncture on the quality of life in women with irritable bowel syndrome