Irritable Bowel Syndrome (IBS) Clinical Trial
Official title:
The Effects of Human Milk Oligosaccharides on Faecal Microbiota, Gastrointestinal Symptoms, Mucosal Immunity and Barrier Function in Irritable Bowel Syndrome: a Parellell, Double-blind, Randomised, Placebo-controlled Study
The study is a randomised, placebo-controlled, double-blind parallel study in IBS patients. A
total of 60 adult patients diagnosed with IBS-C, -D or -A/M according to Rome IV criteria
will be included. The participants will be randomized into one of three groups consuming
either HMO (two groups) or placebo (one group).
The primary objective of the study is to establish the effect of HMOs on the faecal
microbiota in IBS patients. Secondary objectives are to assess the effect on gastrointestinal
symptoms, mucosal immunity, gut barrier function, quality of life, and anxiety and
depression.
n/a
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