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Iron Deficiency clinical trials

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NCT ID: NCT03377777 Completed - Anemia Clinical Trials

The Effect of Anemia in Infancy on the Microbiome and Systemic Metabolism

Start date: August 1, 2014
Phase: N/A
Study type: Observational

Serum and fecal samples were collected from infants at either 6-7 m of age or 12-13 m of age. Serum and feces were analyzed locally for hemoglobin status or evidence of parasites, and standard of care was provided. Excess serum was transported to UC Davis for metabolomics analysis and the University of Hohenheim for iron status assessment and measurement of inflammatory markers. Fecal samples were transported to UC Davis for measurement of the microbiome structure and function.

NCT ID: NCT03359447 Recruiting - Anemia Clinical Trials

Iron Deficiency Anemia, Iron Supplementation and Genomic Stability in Infants

Start date: August 1, 2017
Phase: Phase 4
Study type: Interventional

This study compares weekly versus daily administration of iron for prevention of anemia in 6 months old infants. One third of the infants that are exclusively breast fed will not receive iron, the second third will receive iron weekly and the last third will receive iron daily. Half of the infants that take infant formula will receive iron weekly and the other half will receive iron daily.

NCT ID: NCT03357510 Completed - Iron-deficiency Clinical Trials

The Effect of the Prebiotic Galacto-oligosaccharide on Iron Absorption With Micronutrient Powders in Kenyan Infants

Start date: April 16, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether single doses of the prebiotic galacto-oligosaccharide (GOS) added to iron-fortified meals with micronutrient powders increase iron absorption compared to a 3 weeks pre-feeding of GOS.

NCT ID: NCT03355287 Not yet recruiting - Clinical trials for Iron Deficiency Anemia

Iron Status in Infants in Ethiopia.

Start date: November 2018
Phase: N/A
Study type: Interventional

To assess the impact of soil iron intake from teff flour on iron status in infants in Debre Zeit, Ethiopia.

NCT ID: NCT03353662 Not yet recruiting - Iron-deficiency Clinical Trials

Sub Regional Micronutrient Survey in Ethiopia

Start date: September 2018
Phase:
Study type: Observational

To conduct a sub-regional micronutrient survey (SRMNS) assessing the prevalence of vitamin A, Zn, and Fe status in the country

NCT ID: NCT03344523 Not yet recruiting - Clinical trials for Chronic Heart Failure

Evaluating Iron Protein Succinylate Oral Solution in Treating Chronic Heart Failure and Iron Deficiency

Start date: January 2018
Phase: Phase 4
Study type: Interventional

This study aims to evaluate the effect of standard heart failure therapy plus oral solution with protein succinylate iron compared to placebo on the primary end point of 6 minute walk distance at 24th week in patients with chronic ejection fraction reduction heart failure and iron deficiency.

NCT ID: NCT03332602 Completed - Iron-deficiency Clinical Trials

Iron Absorption From Encapsulated Iron Sulphate in Microspheres

Start date: April 4, 2018
Phase: N/A
Study type: Interventional

Food fortification has shown to be efficacious to alleviate the burden of micronutrient deficiencies. Ensuring the bioavailability of iron and maintaining the sensory quality and stability of the fortified food and other added micronutrients remains a challenge. Soluble iron compounds cause minor organoleptic changes in foods but their bioavailability in man is rather low. Water-soluble iron compounds, such as ferrous sulphate (FeSO4), are the compounds in which the iron is most bioavailable; however, they often cause unfavorable sensory changes. Encapsulation of iron has excellent potential for overcoming unwanted sensory changes and iodine losses in salt, while maintaining acceptable bioavailability. In the present project, we would like to investigate the iron bioavailability from a new formulation of encapsulated iron sulphate based on hyaluronic acid (HA) and a polymer from the eudragit family.

NCT ID: NCT03325270 Completed - Iron-deficiency Clinical Trials

Effect of Prebiotics on Iron Absorption in Women With Low Iron Stores

Fe_GOS_1
Start date: January 10, 2018
Phase: N/A
Study type: Interventional

Rationale: According to the WHO, iron deficiency is still the most common and widespread nutritional disorder in the world. Current iron supplements have limitations in terms of bioavailability and tolerability. Prebiotic fibers, such as galacto-oligosaccharides (GOS), selectively enhance growth of beneficial colonic bacteria. Prebiotics in general enhance the production of short-chain fatty acids (SCFAs) and thereby decrease luminal pH. Through the reduction in colonic pH, prebiotics can enhance absorption of minerals such as calcium and magnesium and they have been proposed to potentially improve iron absorption as well. The primary objective of this study is to investigate the effect of an addition of GOS to an iron supplement on iron absorption in iron deplete, healthy, normal weight women.

NCT ID: NCT03305705 Not yet recruiting - Fatigue Clinical Trials

Effect of Iron on Cerebral Dopamine Receptor Density in Non-anaemic Premenopausal Women With Low Ferritin and Fatigue

Start date: October 23, 2017
Phase: Phase 4
Study type: Interventional

This study investigates the effect of intravenous iron substitution in non-anaemic premenopausal women with iron deficiency on: - Changes in the cerebral Dopamine (DA) receptor density after iron substitution, shown by brain PET - Reduction of fatigue and other neuropsychological symptoms after iron supplementation

NCT ID: NCT03284840 Completed - Clinical trials for Vitamin D Deficiency

Adults Nutrition as a Protective or Health-risk Factor

NUTRIHEALTH
Start date: June 1, 2017
Phase:
Study type: Observational

To obtain up-to-date data on nutrient intakes in adults, a national dietary survey - the EU Menu study will be conducted during 12 consecutive months in 2017/2018, providing data on the consumption of foods and enabling the assessment of energy and macronutrient intakes. Participating subjects will be invited to NUTRIHEALTH study for assessment for micronutrient status (focusing into vitamin D, folic acid, vitamin B12, and iron) and medical examination, in which thyroid size will be aslo measured, to investigated thyroid epidemiology in Slovenia.