Clinical Trials Logo

Iron Chelation clinical trials

View clinical trials related to Iron Chelation.

Filter by:
  • None
  • Page 1

NCT ID: NCT04435028 Completed - Breast Cancer Clinical Trials

Ketotifen: as a Cardioprotective Agent in Breast Cancer Patients Receiving Anthracycline-containing Chemotherapy

Start date: January 14, 2019
Phase:
Study type: Observational

The objective of our study was to evaluate the expected cardioprotective effects of ketotifen due to its activity as an iron-chelating agent previously uncovered by us in the in vitro chemical test which included in the study, when used in patients receiving anthracyclines for the treatment of breast cancer. The study was a randomized : , prospective controlled trial : , and the patients were identified by coded numbers to maintain privacy. Eligible patients (111) fulfilled the criteria. Control Group: 55 patients received their standard therapy (anthracycline-containing chemotherapy without ketotifen). Ketotifen Group: 56 patients received anthracycline-containing chemotherapy plus ketotifen as a cardioprotective agent. Ketotifen will be given orally as one tablet (1 mg/tablet) 3 times daily, before and during the chemotherapeutic cycle for 6 cycles of treatment. Blood samples were obtained from all patients, and echocardiography two times for each patient at baseline and after 6 months (EF%).

NCT ID: NCT02083575 Not yet recruiting - Thalassemia Major Clinical Trials

Role of Vitamin C to Augment Iron Chelation With DFP or DFX

Start date: April 2014
Phase: Phase 2/Phase 3
Study type: Interventional

role of Vit C to Augment iron chelation with DFP or DFX in thalassemic patients.

NCT ID: NCT01927913 Withdrawn - Metabolic Diseases Clinical Trials

Treatment of Iron Overload Requiring Chelation Therapy

Start date: November 20, 2014
Phase: Phase 2
Study type: Interventional

The purpose of this open-label study is to assess liver iron concentration using MRI imaging in subjects with beta-thalassemia when administered with either SPD602 or deferasirox for the treatment of chronic transfusional iron overload.