Uveitis Clinical Trial
Official title:
Screening Study for the Evaluation and Diagnosis of Potential Research Subjects With Ocular Inflammatory or Immunologic Diseases
This screening protocol is designed to facilitate patient recruitment to National Eye
Institute (NEI) clinical research studies. Patients must meet specific requirements of a
research study; this protocol serves as a first step for admitting patients to an appropriate
program.
Candidates may have a diagnosed or undiagnosed eye condition. They will be screened with a
medical history, physical examination, eye examination and blood test. Other screening
procedures may include routine laboratory tests, non-invasive imaging, and questionnaires.
The eye examination includes measurement of eye pressure and dilation of the pupils to fully
examine the lens, vitreous and retina. Specialized eye tests will be done only if needed to
determine eligibility for a specific study. When the screening is completed, patients will be
informed of their options to participate in a study. Patients who are found ineligible for a
current study will be informed of alternative treatments or options. No treatment is offered
under this protocol.
This protocol is designed for the screening of patients with either diagnosed or undiagnosed
conditions, and serves as a first step for individuals who may be eligible, and wish to
participate in NEI- National Eye Institute clinical research studies.
Each individual will be thoroughly evaluated during the screening process to determine if
they are suitable candidates for inclusion in any of the NEI ongoing studies. The screening
evaluation will include past and current medical histories, and an appropriate physical
examination. Other routine diagnostic procedures and tests may also be completed in order to
help determine a subject's eligibility. These tests and procedures are of minimal risk and
will be described in more detail in section III: "Study Procedures". Once the screening
process is completed and their eligibility is assessed, the subjects will be informed of
their options to participate in one or more of the current clinical research studies. If no
appropriate protocol is identified, recommendations for other treatment options may be given
to the individual, their primary doctor, or referring physician.
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Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT04101604 -
Biomarkers of Common Eye Diseases
|
||
Active, not recruiting |
NCT04704609 -
Imaging Quantification of Inflammation (IQI)
|
||
Completed |
NCT03173144 -
Chronic Inflammatory Disease, Lifestyle and Treatment Response
|
||
Withdrawn |
NCT01280669 -
Intravitreal Sirolimus as Therapeutic Approach to Uveitis
|
Phase 2 | |
Terminated |
NCT02907814 -
Measurement of Anterior Chamber Cell Grading Using Ocular Coherence Tomography
|
N/A | |
Active, not recruiting |
NCT02252328 -
Use of Simvastatin as a Steroid Sparing Agent for Uveitis Patients
|
Phase 2/Phase 3 | |
Completed |
NCT04183387 -
Simvastatin in Uveitis
|
Phase 2 | |
Completed |
NCT01983488 -
Clinical Outcome in Uveitis
|
||
Withdrawn |
NCT00499551 -
A Phase I/IIa Study for the Treatment of Uveitis With Iontophoresis
|
Phase 1/Phase 2 | |
Terminated |
NCT00114062 -
Study to Treat Uveitis Associated Macular Edema
|
Phase 2 | |
Completed |
NCT00132691 -
Multicenter Uveitis Steroid Treatment (MUST) Trial
|
Phase 4 | |
Completed |
NCT00476593 -
Retinal OCT and (mfERG) Related to Age, Sex, and the Use of Anti-inflammatory Medications
|
N/A | |
Completed |
NCT00001867 -
Effect of Pregnancy on Uveitis
|
N/A | |
Completed |
NCT00379275 -
Eye and Immunogenetic Features of Sarcoidosis
|
N/A | |
Active, not recruiting |
NCT03828019 -
Adalimumab vs. Conventional Immunosuppression for Uveitis Trial
|
Phase 3 | |
Terminated |
NCT01939691 -
Macular Edema Nepafenac vs. Difluprednate Uveitis Trial
|
Phase 4 | |
Active, not recruiting |
NCT03889860 -
Objective Choroidal Thickness Measurements in Uveitis
|
||
Completed |
NCT00070759 -
Daclizumab to Treat Non-Infectious Sight-Threatening Uveitis
|
Phase 2 | |
Recruiting |
NCT05486468 -
The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment
|
Phase 3 | |
Active, not recruiting |
NCT05385757 -
UNICORNS: Uveitis in Childhood Prospective National Cohort Study
|