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Intravascular Ultrasound clinical trials

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NCT ID: NCT06080919 Recruiting - Clinical trials for Coronary Artery Disease

Plaque Modification And Impact On Microcirculatory Territory After Drug-Coated Balloon Percutaneous Coronary Intervention (PLAMI).

PLAMI
Start date: September 12, 2022
Phase: N/A
Study type: Interventional

Coronary artery disease (CAD) is one of the most common causes of mortality worldwide. Despite drug eluting stents (DES) are the most common treatment strategy, drug-coated balloons (DCB) represent an appealing alternative to DES as they eliminate the risk of stent thrombosis and do not leave any type of metallic structure in the vessel wall. However, the evidence of the vessel wall healing processes, plaque remodeling, plaque composition and impact on coronary microcirculation after PCI with DCB have not yet been characterized. The purpose of this study is to assess the changes in percentage atheroma volume evaluated by intravascular ultrasound (IVUS) in patients undergoing DCB-PCI.

NCT ID: NCT05007535 Active, not recruiting - Clinical trials for Coronary Artery Disease

Tissue Characterization and Primary Percutaneous Coronary Intervention Guidance Using Intravascular Ultrasound

SPECTRUM
Start date: November 10, 2020
Phase:
Study type: Observational

This prospective, single arm, observational cohort study is designed to assess the safety and efficacy of (high-definition) intravascular ultrasound (HD-IVUS) as guidance for primary percutaneous coronary intervention (PCI) and to assess culprit lesion plaque characteristics and thrombus morphology in patients with ST-elevation myocardial infarction (STEMI). Objectives: - To assess clinical outcomes after IVUS-guided primary PCI in STEMI patients. - To assess IVUS-guided optimization in STEMI patients. - To assess culprit lesion plaque characteristics in STEMI patients with HD-IVUS. - To assess and quantify thrombus in STEMI patients with HD-IVUS. - To explore HD-IVUS derived predictors for clinically relevant aspiration thrombectomy.

NCT ID: NCT03574636 Recruiting - Clinical trials for Optical Coherence Tomography

OCT vs IVUS vs QCA to Guide Moderate-to-severe Calcified Lesion Stent Implantation

Start date: October 18, 2019
Phase: N/A
Study type: Interventional

This study is a prospective, multi-center, randomized controlled clinical trial, aims to assess the safety and effectiveness of Optical Coherence Tomography or Intravascular Ultrasound or Quantitative Coronary Analysis to guide Firehawk stent implantation , and compared the treatment of moderate-to-severe calcified lesion in coronary artery.

NCT ID: NCT03461367 Active, not recruiting - Clinical trials for Coronary Heart Disease

CTO Registry From Insight of IVUS in Fuwai Hospital

FWCTO
Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

To evaluate the long-term outcome of chronic total occlusion (CTO) patients underwent contemporary percutaneous coronary intervention (PCI) techniques, we design this single-center, large-sample, prospective registry with five-year clinical follow-up, based on the intravascular ultrasound (IVUS) finding.

NCT ID: NCT01223586 Completed - Clinical trials for Acute Coronary Syndrome

Extended Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome

Ex JAPAN-ACS
Start date: November 2010
Phase: N/A
Study type: Observational

The objective of this study is to verify the relationship between coronary plaque regression and cardiovascular prevention in long term follow up of the Japan Assessment of Pitavastatin and Atorvastatin in Acute Coronary Syndrome (JAPAN-ACS) study [NCT00242944]. In addition, the effect of serum lipid levels or different type of statins on cardiovascular prevention will also be examined.