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Intraoperative Analgesia clinical trials

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NCT ID: NCT06131905 Not yet recruiting - Magnesium Clinical Trials

Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in Colonoscopy

Start date: January 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

Colonoscopy is one of the most commonly performed outpatient procedures throughout the world as a screening, diagnostic, and therapeutic tool to evaluate the large intestine from the distal rectum to the cecum.Propofol is the most commonly used hypnotic agent in sedation during endoscopic procedures for its advantages of fast onset and quick recovery. However, propofol may cause respiratory depression and cardiovascular events, which are easier to appear in cases of old age and high speed administration of propofol.Magnesium is a non-specific calcium channel inhibitor and a non-competitive N-methyl-D-aspartate(NMDA)receptor antagonist, which has analgesic and mild sedative properties .

NCT ID: NCT06104059 Recruiting - Clinical trials for Intraoperative Analgesia

NOL Guided Analgesia During Elective Laparoscopic Surgery Under General Anesthesia

NOLGADELS
Start date: October 16, 2023
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the hypothesis that the intraoperative use of the nociception level index NOL can reduce opioid consumption in adult patients undergoing elective laparoscopic surgeries under general anesthesia, as well as to explore its effect on post-operative pain and patient recovery.

NCT ID: NCT04988776 Completed - Postoperative Pain Clinical Trials

PECS II Versus ICBN Block Plus SCNB for AV Fistula Creation in CRF Patients

Start date: February 1, 2020
Phase: Phase 1/Phase 2
Study type: Interventional

Brachial plexus block (BPB) is often utilized for proximal arm arteriovenous access creation. However, the medial upper arm and axilla are often inadequately anesthetized, as the Intercostobrachial nerve (which provides sensory supply to the axilla, upper medial arm, and a small area at the upper lateral chest) is not a component of the brachial plexus. This requires repeated, an intraoperative local anesthetic (LA) supplementation up to conversion into GA. The intercostobrachial nerve (ICBN) is a purely sensory nerve that arises primarily from the second intercostal nerve (T2) with occasional contribution from T3. Therefore, It is not a component of the brachial plexus and is not anesthetized by brachial plexus blockade. The ICBN can be blocked together with other nerves, such as the pectoral, intercostal, and long thoracic nerves in a recently described technique named pectoral nerves block type II (PECS II ).In this thesis, investigators compared the use of the PECS II block and ICBN block as a supplement to supraclavicular brachial plexus block for providing complete anesthesia of the upper arm for fistula creation surgery.

NCT ID: NCT03170726 Active, not recruiting - Clinical trials for Intraoperative Analgesia

Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth

Start date: May 15, 2017
Phase: N/A
Study type: Interventional

This study was planned to evaluate the analgesic efficacy of preemptive intravenous (iv) ibuprofen on pain occurring during and after the mandibular third molar surgeon