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Intraocular Retinoblastoma clinical trials

View clinical trials related to Intraocular Retinoblastoma.

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NCT ID: NCT03932786 Recruiting - Cancer Survivor Clinical Trials

Studying Health Outcomes After Treatment in Patients With Retinoblastoma

RIVERBOAT
Start date: January 24, 2019
Phase:
Study type: Observational

This trial studies health outcomes after treatment in patients with retinoblastoma. Gathering health information over time from patients and family members through vision assessments, samples of tissue and saliva, and questionnaires may help doctors learn more about what causes retinoblastoma, identify long-term health outcomes for patients with retinoblastoma, and find out which therapies may be the best for treating retinoblastoma

NCT ID: NCT03866460 Active, not recruiting - Hearing Loss Clinical Trials

Determining Whether Intra-Arterial Carboplatin Causes Hearing Loss in Children

Start date: March 6, 2019
Phase:
Study type: Observational

The purpose of this study is to find out how often hearing loss occurs in patients with retinoblastoma after receiving treatment with intra-arterial carboplatin.

NCT ID: NCT00889018 Active, not recruiting - Clinical trials for Intraocular Retinoblastoma

Trial Comparing Two Carboplatin Doses in Groups C and D Intraocular Retinoblastoma

Start date: April 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether an increase in the dose of carboplatin in treatment of advanced intraocular (group C and D) retinoblastoma helps in avoiding radiotherapy and improves the rate of globe salvage.

NCT ID: NCT00690469 Completed - Clinical trials for Intraocular Retinoblastoma

Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers

Start date: June 2, 2008
Phase:
Study type: Observational

This laboratory study is looking at genetic mutations and environmental exposure in young patients with retinoblastoma and in their parents and young healthy unrelated volunteers. Gathering information about gene mutations and environmental exposure may help doctors learn more about the causes of retinoblastoma in young patients.

NCT ID: NCT00335738 Completed - Clinical trials for Intraocular Retinoblastoma

Vincristine, Carboplatin, and Etoposide or Observation Only in Treating Patients Who Have Undergone Surgery for Newly Diagnosed Retinoblastoma

Start date: December 2005
Phase: Phase 3
Study type: Interventional

This phase III trial is studying vincristine, carboplatin, and etoposide to see how well they work compared to observation only in treating patients who have undergone surgery for newly diagnosed retinoblastoma. Drugs used in chemotherapy, such as vincristine, carboplatin, and etoposide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) after surgery may kill any tumor cells that remain after surgery. Sometimes, after surgery, no additional treatment is needed for the tumor until it progresses. In this case, observation may be sufficient.

NCT ID: NCT00079417 Completed - Clinical trials for Intraocular Retinoblastoma

Neoadjuvant Carboplatin and Vincristine and Standard Local Ophthalmic Therapy in Treating Patients With Intraocular Retinoblastoma

Start date: December 26, 2005
Phase: Phase 3
Study type: Interventional

This phase III trial is studying how well giving carboplatin and vincristine together with standard local ophthalmic therapy works in treating children with intraocular retinoblastoma. Drugs used in chemotherapy, such as carboplatin and vincristine, work in different ways to stop tumor from dividing so they stop growing or die. It is not yet known whether neoadjuvant chemotherapy combined with standard local ophthalmic therapy is effective in treating intraocular retinoblastoma.

NCT ID: NCT00072384 Completed - Clinical trials for Intraocular Retinoblastoma

Systemic Chemotherapy and Subtenon Carboplatin, and Local Ophthalmic Therapy in Children With Intraocular Retinoblastoma

Start date: April 16, 2007
Phase: Phase 3
Study type: Interventional

Phase III trial to determine the effectiveness of combining systemic chemotherapy and subtenon carboplatin with ophthalmic therapy in treating children who have intraocular retinoblastoma. Drugs used in chemotherapy, such as vincristine, carboplatin, and etoposide, work in different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether systemic chemotherapy and subtenon (under the conjunctiva of the eye) carboplatin combined with ophthalmic therapy is effective in treating intraocular (within the eyeball) retinoblastoma.