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Intraocular Pressure clinical trials

View clinical trials related to Intraocular Pressure.

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NCT ID: NCT01174342 Completed - Clinical trials for Intraocular Pressure

Effect of Child Delivery on Intraocular Pressure

Start date: August 2010
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the effect of child delivery on the intraocular pressure in healthy women.

NCT ID: NCT01159340 Completed - Clinical trials for Intraocular Pressure

Icare Versus Haag-Streit Applanation Tonometer

Start date: May 2009
Phase: N/A
Study type: Observational

The clinical performance of Icare ONE Tonometer TA02 was compared to a Goldmann type applanation tonometer (Haag-Streit). Data was collected according to ANSI Z80.10-2003 (ISO 8612.2) standard. Subjects were eligible for the study if they had no exclusion criteria specified in the ANSI/ISO standard. One eye from 260 subjects was selected for the study. The minimum sample size according to the standard is 150. One eye of each subject was selected for the study by an investigator, based on the history of the patient, results of an external examination of the eye with slit lamp, keratometry readings, and prior knowledge of the intraocular pressure (IOP) range. The Icare ONE Tonometer TA02 in comparison to the reference tonometer (Goldmann type tonometer).

NCT ID: NCT01144494 Completed - Clinical trials for Intraocular Pressure

Aqueous Humor Dynamics and Brimonidine

Brimonidine
Start date: August 1, 2010
Phase: Early Phase 1
Study type: Interventional

This single-center, investigator-masked, crossover study is designed to investigate the circadian rhythms of aqueous humor dynamics in human subjects with ocular hypertension (OHT) before and after intervention with a commonly used ocular hypotensive medication, brimonidine for six weeks.

NCT ID: NCT00884039 Terminated - Clinical trials for Intraocular Pressure

Anecortave Acetate Injection to Treat Steroid-responsive Intraocular Pressure Increase in Cornea Transplant Patients

Start date: May 2009
Phase: N/A
Study type: Interventional

This study will investigate the use of anecortave acetate injection to reduce intraocular pressure (IOP) in corneal transplant recipients who are experiencing steroid-associated pressure control problems. Alternative methods of IOP control have been shown to entail serious risks. For example, reduction of topical steroids increases the risk of graft rejection, and use of glaucoma medications or glaucoma surgery increases the risk of graft failure. This study is designed to have sufficient power to detect whether a single injection can induce a clinically significant IOP reduction.

NCT ID: NCT00864578 Withdrawn - Clinical trials for Primary Open Angle Glaucoma

Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Maximum Tolerated Medical Therapy

Start date: April 2009
Phase: N/A
Study type: Observational

Elevated intraocular pressure is still the main risk factor for development and progression of glaucoma. Several drugs exist on the market that may decrease IOP in glaucomatous patients. However, some patients cannot reach the target pressure despite a multitherapy with a combination of drugs, and are therefore addressed to surgical treatments. Forskolin is a natural compound that is a receptor-independent adenyl-cyclase activator, that increases intracellular cAMP. It has been shown to be able to decrease IOP after topical application, by a mechanism that is not used by the other drugs. Aim of the present study is to see whether a food supplement containing forskolin (KRONEK) has any effect on the IOP of POAG patients that cannot reach their target pressure, and are therefore on the waiting list for surgical intervention.

NCT ID: NCT00863811 Withdrawn - Clinical trials for Primary Open Angle Glaucoma

Effects of Forskolin on Intraocular Pressure in Glaucomatous Patients Under Treatment With Either Beta-blockers or Prostaglandins Eye Drops

Start date: April 2009
Phase: N/A
Study type: Observational

Elevated intraocular pressure is still the main risk factor for development and progression of glaucoma. Several drugs exist on the market that may decrease IOP in glaucomatous patients. However, some patients cannot reach the target pressure despite a multitherapy with a combination of drugs, and are therefore addressed to surgical treatments. Forskolin is a natural compound that is a receptor-independent adenyl-cyclase activator, that increases intracellular cAMP. It has been shown to be able to decrease IOP after topical application, by a mechanism that is not used by the other drugs. Aim of the present study is to see whether oral administration of a food supplement containing forskolin (KRONEK) has any effect on the IOP of POAG patients with stable IOP obtained by treatment with either beta-blockers or prostaglandins.

NCT ID: NCT00863018 Completed - Glaucoma Clinical Trials

Corneal Endothelium After Glaucoma Surgery

Start date: August 2003
Phase: N/A
Study type: Observational

The purpose of this trial is to study the change in corneal endothelial cell after glaucoma surgery, non-contact specular microscopic examination is performed for the patients who underwent glaucoma surgery; trabeculectomy and Ahmed glaucoma valve implant surgery prospectively. Change in corneal endothelial cell density, hexagonality, and coefficient of variation of cell area will be analyzed and compared to the baseline and between the types of the surgeries.

NCT ID: NCT00856141 Completed - Clinical trials for Intraocular Pressure

Set up for in-Vivo Measurement of Dynamic Intraocular Pressure (IOP)

Start date: January 2006
Phase: N/A
Study type: Interventional

In this modern era, surgeons prefer to perform emulsification through small micro incisions. To accomplish this safely, surgeons raise irrigation bottle heights or use forced infusion systems.We believe that this sustained rise in the IOP during micro-incision phacoemulsification for a substantial period could be detrimental to the ocular structures. Therefore, intra-operative IOP pertaining to micro-incision cataract surgery is an emerging concern. Conventional systems for measuring IOP generate an isolated graph of continuous pressure recording. Interpretation of the IOP fluctuations from these graphs requires a two step superimposition approach to characterize the IOP changes.

NCT ID: NCT00852774 Withdrawn - Clinical trials for Intraocular Pressure

Steep Trendelenburg Positioning on Intra-Ocular Pressure During Surgery for Endometrial Robotics Versus Laparotomy

Start date: May 2009
Phase: N/A
Study type: Observational

The purpose of this study is to assess changes of intra-ocular pressure (IOP) and examine preoperative facts affecting IOP in endometrial cancer patients undergoing robotic hysterectomy compared to laparotomy.

NCT ID: NCT00837226 Withdrawn - Clinical trials for Intraocular Pressure

Effects of Weight Loss From Bariatric Surgery on Intraocular Pressure (IOP)

IOP
Start date: September 2010
Phase: N/A
Study type: Observational

The purpose of this study is to determine if there is an effect on the eye pressure from extreme weight loss by bariatric procedures. The hypothesis is that excess fat in the orbit of the eye compresses on the outflow system, which causes an elevated eye pressure. This can have many consequences, including the risk for glaucoma. We hope to establish if there is an effect between eye pressure and weight.