Lenvatinib for Unresectable Intrahepatic Cholangiocarcinoma

Status Withdrawn

Clinical Trial Summary

The purpose of this study is to evaluate the efficacy and safety of lenvatinib for patients with unresectable intrahepatic cholangiocarcinoma

Clinical Trial Description

Lenvatinib was non-inferior to sorafenib in overall survival in untreated advanced hepatocellular carcinoma.No study has evaluated the efficacy and safety of lenvatinib in unresectable intrahepatic cholangiocarcinoma. Thus, the investigators carried out this prospective study to find out it. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03801499
Study type	Interventional
Source	Sun Yat-sen University
Contact
Status	Withdrawn
Phase	Phase 2
Start date	September 1, 2018
Completion date	December 2019

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05678218` - Preoperative Evaluation of Lymph Nodes of Cholangiocarcinoma
Active, not recruiting	`NCT03781934` - A Study to Evaluate MIV-818 in Patients With Liver Cancer Manifestations	Phase 1/Phase 2
Completed	`NCT01938729` - Hepatic Arterial Infusion With Floxuridine and Dexamethasone in Combination With Gemcitabine as Adjuvant Treatment After Resection of Intrahepatic Cholangiocarcinoma	Phase 1
Completed	`NCT03230318` - Derazantinib in Subjects With FGFR2 Gene Fusion-, Mutation- or Amplification- Positive Inoperable or Advanced Intrahepatic Cholangiocarcinoma	Phase 2
Recruiting	`NCT06239532` - HAIC Sequential TAE Combined With Tislelizumab and Surufatinib in Unresectable Intrahepatic Cholangiocarcinoma	Phase 2
Not yet recruiting	`NCT05535647` - Second Line Therapy for Advanced Intrahepatic Cholangiocarcinoma	Phase 2
Not yet recruiting	`NCT05009953` - Study of Irinotecan Liposome Injection in Patients With Advanced Biliary Tract Cancer	Phase 2
Terminated	`NCT02254681` - Low-Dose Radiation Therapy to the Whole Liver With Gemcitabine and Cisplatin in IHC	Phase 2
Active, not recruiting	`NCT01954745` - A Phase II Study of Cabozantinib (XL-184) Monotherapy in Patients With Advanced Cholangiocarcinoma After Progression on First or Second Line Systemic Therapy	Phase 2
Completed	`NCT01347333` - Stereotactic Body Radiotherapy for Liver Tumors	N/A
Active, not recruiting	`NCT04526106` - REFOCUS: A First-in-Human Study of Highly Selective FGFR2 Inhibitor, RLY-4008, in Patients With ICC and Other Advanced Solid Tumors	Phase 1/Phase 2
Recruiting	`NCT05285358` - Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases	Phase 1
Completed	`NCT03320980` - RALPPS in Patients With Hilar and Intrahepatic Cholangiocarcinoma	N/A
Withdrawn	`NCT05019677` - GP Chemotherapy in Combination With Tislelizumab and Ociperlimab as First-line Treatment in Advanced BTC	Phase 2
Completed	`NCT05489692` - HAIC Plus Targeted Therapy and/or PD-1 Inhibitors for Unresectable Intrahepatic Cholangiocarcinoma
Recruiting	`NCT06101277` - Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)	N/A
Active, not recruiting	`NCT01917370` - VEGF Signaling Promotes Cell Growth and Metastasis in Intrahepatic Cholangiocarcinoma in a VEGF Receptor Mediated Pathway	N/A
Withdrawn	`NCT01775280` - Response of Hepatic Tumors to Radioembolization	Phase 2
Not yet recruiting	`NCT05342194` - Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study	Phase 3
Active, not recruiting	`NCT05781958` - Cadonilimab Combined With Gem/Cis as First Line Therapy in Patients With Advanced ICC	Phase 2