Evaluation of 4-Factor PCC in DOAC-associated Intracranial Hemorrhage

Status Recruiting

Clinical Trial Summary

Intracranial hemorrhage (ICH) can occur due to traumatic and spontaneous events.1 The incidence of non-traumatic, spontaneous ICH is approximately 40,000 to 67,000 cases per year while the incidence of traumatic brain injury (TBI) is nearly 1.7 million annually

Clinical Trial Description

The authors found that AC use preinjury was associated with ICH progression, immediate neurosurgery intervention, and death after initial scan. AC use has also been associated with worse functional outcomes, and patients are less likely to be discharged home compared to those without AC use prior to injury.6 With increasing prevalence of AC, hospitals are seeing admissions for ICH, making knowledge of optimal AC reversal essential. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06096051
Study type	Observational
Source	Methodist Health System
Contact	Bethany Brauer, MPH
Phone	214-947-1281
Email	MHSIRB@mhd.com
Status	Recruiting
Phase
Start date	July 13, 2023
Completion date	July 13, 2024

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