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Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis — CAPTIVA  

Stroke Clinical Trial

Official title:
Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis (CAPTIVA)

Clinical Trial Summary

The primary goal of the trial is to determine if the experimental arms (rivaroxaban or ticagrelor or both) are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death.

Clinical Trial Description

The proposed study is relevant to public health because narrowing of brain arteries is one of the most common causes of stroke worldwide. Compelling evidence suggests novel antithrombotic medications could reduce the rate of stroke in patients with narrowed brain arteries. The proposed study will directly compare novel antithrombotic medications to standard care antiplatelet medications for preventing stroke and death from vascular causes in patients with narrowed brain arteries. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05047172
Study type Interventional
Source University of Florida
Contact Stephanie McLaren, BSN, RN
Phone 888-351-7776
Email CAPTIVA-Study@ufl.edu
Status Recruiting
Phase Phase 3
Start date August 2, 2022
Completion date May 31, 2027
View Details
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