IDH in Diabetic Haemodialysis Patients and Association With Dialytic Age

Intra-dialytic Hypotension Clinical Trial

Official title: Intradialytic Hypotension in Diabetic Haemodialysis Patients and Its Association With Dialytic Age

Status Not yet recruiting

Clinical Trial Summary

Intradialytic hypotension (IDH ) is a serious and the most frequent complication of hemodialysis of the hemodialysis .Diabetes is associated with autonomic neuropathy which contribute to intradialytic hypotension

Clinical Trial Description

Intradialytic hypotension (IDH ) is a serious and the most frequent complication of hemodialysis of the hemodialysis.Intradialytic hypotension is a decrease in systolic BP by ≥20 mm Hg or a decrease in mean arterial pressure of 10 mm Hg associated with symptoms like cramps, dizziness, headache ,nausea and vomiting according to The National Kidney Foundation.Intradialytic hypotension occurs during 20%-30% of hemodialysis sessions. It is associated with poor long-term outcomes. Patients with Intradialytic hypotension show increased morbidity and mortality.The etiology of Intradialytic hypotension is multifactorial and depends on patient-related factors, as well as on complications related to the dialysis procedure. The main causes Intradialytic hypotension have been reported to be acute hypovolemia during ultrafiltration and inadequate compensatory mechanisms such as left ventricular dysfunction, inappropriate plasma refilling ,Impaired vasoconstriction induced by dysregulation of autonomic nervous system.

Diabetes mellitus is the most common cause of chronic renal failure .Diabetic patients are more prone to cardiovascular diseases than non-diabetics .Although diabetes is in relation with hypertension ,It is associated with autonomic neuropathy which contribute to intradialytic hypotension . Recent researches suggested that older age and long dialytic age may incease risk of intradialytic hypotension. ;

Related Conditions & MeSH terms

• Hypotension
• Intra-dialytic Hypotension

• NCT number: NCT03870594
• Study type: Observational
• Source: Assiut University
• Contact: Mahmoud fawzy
• Phone: 201276366168
• Email: mahmoudfawzy2490@yahoo.com
• Status: Not yet recruiting
• Start date: April 2019
• Completion date: July 2019