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Intestinal Obstruction clinical trials

View clinical trials related to Intestinal Obstruction.

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NCT ID: NCT04174807 Recruiting - Gastroschisis Clinical Trials

Prospective Study of Antenatal Diagnostic Criteria for Digestive Complications of Gastroschisis

LaparoDAN
Start date: December 1, 2019
Phase:
Study type: Observational

Gastroschisis is a rare congenital malformation consisting in a right para-umbilical defect of the abdominal wall leading to an evisceration of the abdominal content. About 25% of the cases are associated with intestinal malformation, leading to an increase in peri-natal morbidity and mortality. No prospective study has been able to definitely describe predictive factors for complicated gastroschisis on prenatal ultrasound examinations. The aim of the current study is to prospectively look for US prenatal features predictive of complicated gastroschisis, on a national multicentric cohort. Patients will be included during the 22 weeks of amenorrhea (WA) ultrasound examination, and pre- and postnatal clinical data will be recorded up to the 6th months of the child. Data will then be analysed and compared in the groups of simple or complicated gastroschisis, in order to define pre-natal prognostic factors, to correlate them with specific prognosis, and to might better determine specific strategies for better care of these patients.

NCT ID: NCT03905239 Recruiting - Clinical trials for Small Bowel Obstruction

A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction

ALPROC
Start date: April 1, 2019
Phase: N/A
Study type: Interventional

Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically. However, the choice between these two approaches can be difficult due to the absence of specific signs. The objective of this study is to evaluate the clinical impact of a procalcitonin-based algorithm.

NCT ID: NCT03786159 Recruiting - Surgical Adhesions Clinical Trials

National Snapshot Study Adhesive Small Bowel Obstruction (ASBO)

Start date: April 1, 2019
Phase:
Study type: Observational [Patient Registry]

Over 63-90% of patients develop peritoneal adhesions after abdominal or pelvic surgery. Which makes it the most common complication after abdominal or pelvic surgery. Adhesions comprise a lifelong risk of adhesion related complications.The most frequent emergency complication of adhesion is an episode of adhesive small bowel obstruction (ASBO). Over 1 in 5 patients experiences at least 1 episode of ASBO in the 10 years following initial abdominal surgery. Despite the high incidence of ASBO, diagnosis and treatment of an episode of ASBO varies greatly between hospitals and even between doctors. Until now, optimal treatment patterns are unknown. The aim of this study is mapping of care for patients with a suspected episode of ASBO. With the collected data new hypothesis will be generated for the ideal diagnostic and therapeutic workflow for patients with a suspicion of an episode of ASBO.

NCT ID: NCT03771508 Recruiting - Clinical trials for Small Intestine Cancer

Prospective Collection of PillCam SB3 Videos and Raw Data Files for Future Developments (SODA)

SODA
Start date: December 13, 2018
Phase:
Study type: Observational

Observational, Multicenter, Post-market, Minimal risk, Prospective data collection of PillCam SB3 videos (including PillCam reports) and raw data files and optional collection of Eneteroscopy reports

NCT ID: NCT03741257 Recruiting - Clinical trials for Intestinal Obstruction Fluid Management With Hypertonic Saline

Comparison Between Two Concentration of Hypertonic Saline in Intestinal Obstruction Surgery

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Background and Rationale : Perioperative fluid management is a challenging issue in surgical care especially in a procedure specific model. Recently hypertonic saline (HS) has the advantage of using the patient's own total body water by drawing interstitial space. Although it still controversial whether HS is associated with benefits in specific patient populations, particularly with respect to site of lesion and illness severity; these data provide insight into therapeutic modalities to curtail ileus formation. Objectives : - Measurement of total volume of fluid infused, the need of inotropic or vasopressor to maintain adequate hemodynamic parameters with assessment of electrolyte disturbances and S.lactate - The incidence rate of surgical complications; infection and anastomotic dehiscence Study population & Sample size : There were no previous trials comparing the two studied groups of the current trial. We expected a small standardized effect size of 0.2. Based on this effect size, 25 subjects will be needed to elicit the difference between the two groups at an alpha level of 0.05 and power of 0.9 (Whitehead et al; 2016).

NCT ID: NCT03260647 Recruiting - Gynecologic Cancer Clinical Trials

Risk Stratified Multidisciplinary Ambulatory Management of Malignant Bowel Obstruction in Gynecological Cancers

MAMBO
Start date: August 4, 2017
Phase:
Study type: Observational

Management of Malignant Bowel Obstruction (MBO) in Patients with Advanced Gynecological Cancers

NCT ID: NCT03150992 Recruiting - Ovarian Cancer Clinical Trials

EDMONd - Elemental Diet in Bowel Obstruction

EDMONd
Start date: July 19, 2017
Phase: N/A
Study type: Interventional

A feasibility study to provide 'proof of concept' of Elemental Diet (ED) as an acceptable/ useful feeding option for patient with inoperable malignant bowel obstruction and to examine the impact of ED on quality of life

NCT ID: NCT03139149 Recruiting - Clinical trials for Small Bowel Obstruction

Comparison of Early Operative Treatment and 48 h Conservative Treatment in Small Bowel Obstruction

COTACSO
Start date: October 11, 2017
Phase: N/A
Study type: Interventional

This study will compare the results of early surgery after 12 h conservative treatment and 48 h conservative treatment of adhesive small bowel obstruction.

NCT ID: NCT01669044 Recruiting - Cirrhosis Clinical Trials

Comparison the Hemodynamics Effects Between Dexmedetomidine and Propofol in Major Abdominal Surgical Patients

Start date: May 2012
Phase: N/A
Study type: Observational

The alpha2 agonist dexmedetomidine is a new sedative agent combined with the analgesic qualities and lack of respiratory depression. Patients sedated with dexmedetomidine could be easily roused, these advances shows dexmedetomidine may be a effective and safe sedative agent. But some studies showed some adversely effects of dexmedetomidine on haemodynamics (such as bradycardia, hypotension), the investigators want to further research the effects of dexmedetomidine on haemodynamics, such as Cardiac Output (CO), Systemic Venous Resistance Index(SVRI), and so on. Propofol is widely used sedative agent in ICU, it also has adversely effects like bradycardia and hypotension, so the investigators want to compare the effect of dexmedetomidine with propofol on haemodynamics after major abdominal surgery. Expect to further research the mechanism of haemodynamics of dexmedetomidine.

NCT ID: NCT01561729 Recruiting - Clinical trials for Gastrointestinal Hemorrhage

Nasogastric/Orogastric Tube Placement Verification Study Using RightSpot pH Indicator to Verify Gastric Acidity

Start date: January 2012
Phase: N/A
Study type: Interventional

This study will evaluate the use of RightBio Metrics' RightSpot device used to determine if there is proper placement of a nasogastric or orogastric tube.