Comparison of Early Operative Treatment and 48 h Conservative Treatment in Small Bowel Obstruction — COTACSO  

Small Bowel Obstruction Clinical Trial

Official title: Comparison of Early Operative Treatment (12 h) and 48 h Conservative Treatment in Acute Small Bowel Obstruction

Status Recruiting

Clinical Trial Summary

This study will compare the results of early surgery after 12 h conservative treatment and 48 h conservative treatment of adhesive small bowel obstruction.

Clinical Trial Description

At the admission patients undergo abdomen x-ray, general and biochemical blood test and computer tomography (CT). After exclusion of indications for an emergency operation, patients are given a water-soluble contrast. Conservative treatment is carring out to 12 hours from admission. All patients with resolution of small bowel obstruction in 12 hours will be excluded from the research. Criteria for obstruction release of conservative treatment 1. No pain 2. Appearance of gas in the colon 3. Decrease of bloating 4. Contrast in the colon. After that, if obstruction is not resolved, randomization is performed. First group undergo surgery. Second group undergo conservative treatment with water-soluble contrast evaluation until 48 hours. In the second group surgery is performed if the conservative treatment is not effective. The results of early and late surgery and the results of conservative treatment in groups will be compared. ;

Related Conditions & MeSH terms

• Intestinal Obstruction
• Small Bowel Adhesion
• Small Bowel Obstruction
• Strangulation of Ileum

• NCT number: NCT03139149
• Study type: Interventional
• Source: Pirogov Russian National Research Medical University
• Contact: Alexander E Tyagunov, MD. Prof
• Phone: +79165022324
• Email: tyagunov1@mail.ru
• Status: Recruiting
• Phase: N/A
• Start date: October 11, 2017
• Completion date: December 31, 2024