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Intestinal Disorder clinical trials

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NCT ID: NCT04587713 Completed - Clinical trials for Bowel Diseases, Inflammatory

Single Dose Bioavailability and Ethnobridging PK Study in Healthy Subjects

Start date: October 16, 2020
Phase: Phase 1
Study type: Interventional

This is a Phase 1, 2-part, open-label study. Part A will be a formulation bridging and food effect study in healthy adult subjects. Part B will be an assessment of pharmacokinetics (PK) in healthy adult Chinese subjects.

NCT ID: NCT04187820 Recruiting - Crohn Disease Clinical Trials

Effect of Acupuncture on Mild to Moderate Active Crohn's Disease

Start date: June 1, 2019
Phase: N/A
Study type: Interventional

To observe the clinical effect of acupuncture on Crohn's disease (CD) and its influence on brain function activity and the TRY-KYN metabolism level, and to screen the brain image markers of acupuncture on CD

NCT ID: NCT03550365 Completed - Inflammation Clinical Trials

Grain Fibre and Gut Health

FIBREFECTS
Start date: January 1, 2011
Phase: N/A
Study type: Interventional

Wholegrain fibre is known to affect on the gut health, but also may cause intestinal discomfort. Thus, many individuals may avoid the consumption of whole grain cereals in spite of their known health benefits, and may in this regard consume more restricted diets. In the preset study the aim was to technologically modify the cereal fibres to improve its usability and to maintain its health beneficial properties. The objective was to investigate intestinal fermentation of grain dietary fibre and associated effects on gut-mediated metabolic health, such as immunological health and adipose tissue function. The hypothesis was that whole grain products maintain their original beneficial health effects and may be better tolerable when the bran is technologically modified. Additionally, it was hypothesized that gut-mediated bioavailability of plant cell wall compounds and their metabolites affect the metabolic health through their immunomodulatory effects.