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Effect of NanoChitosan Impregnated Calcium Hydroxide as an Intracanal Medication on Postoperative Pain Intensity and Bacterial Load Reduction

Intervention Clinical Trial

Official title:
Effect of NanoChitosan Impregnated Calcium Hydroxide Paste as an Intracanal Medication on the Intensity of Postoperative Pain and Bacterial Load Reduction in Necrotic Teeth: A Randomized Controlled Trial

Clinical Trial Summary

This research will study the effect of NanoChitosan impregnated Calcium Hydroxide versus Calcium Hydroxide as an intracanal medication on postoperative pain intensity measured using numerical rating scale (NRS) and bacterial load reduction determined by bacterial counting using agar culture technique after root canal preparation (CFU/ml) in necrotic teeth.

Clinical Trial Description

Primary outcome: Postoperative pain measured using numerical rating scale (NRS) 1. After placement of intracanal medicament at 6, 12, 24 and 48 hours. 2. After root canal obturation at 6, 12, 24 and 48 hours. Secondary outcome: Bacterial load reduction determined by bacterial counting using agar culture technique after root canal preparation (CFU/ml) 1. Sample 1 (S1): after access preparation and pre-instrumentation. 2. Sample 2 (S2): post-instrumentation. 3. Sample 3 (S3): post-intracanal medicament removal at 7 days. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06253247
Study type Interventional
Source Cairo University
Contact Yasmine ElGhannam
Phone +201099978023
Email y.elghannam@outlook.com
Status Not yet recruiting
Phase N/A
Start date April 2024
Completion date June 2024
View Details
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