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Intensive Care (ICU) Myopathy clinical trials

View clinical trials related to Intensive Care (ICU) Myopathy.

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NCT ID: NCT05282576 Completed - Clinical trials for Intensive Care Unit Acquired Weakness

Effect of Neurophysiological Facilitation Techniques in Intensive Care Patients

Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the effect of neurophysiological facilitation techniques on respiratory and functional levels in intensive care patients. Participants were divided into two groups as experimental (n=20) and control (n=20). Conventional physiotherapy, which includes chest physiotherapy, mobilization exercises and range of motion exercises were applied in control group. Neurophysiological facilitation techniques in addition to the conventional physiotherapy program ere applied in experimental group. The functional status, lower and upper extremity muscle strength, grip strength measurements of the patients and the rates of weaning from mechanical ventilation were evaluated before and after treatment. Vital signs, dyspnea and fatigue perception were assessed each day of treatment. Evaluations were analyzed statistically using Statistical Package for the Social Sciences-22 program.

NCT ID: NCT05211661 Recruiting - Respiratory Failure Clinical Trials

Diaphragm Atrophy and Dysfunction in Mechanical Ventilation

DAM
Start date: October 10, 2022
Phase:
Study type: Observational

The gold standard of twitch transdiaphragmatic pressure recordings would ultimately clear the fog around the rate of development of Ventilator induced Diaphragm Dysfunction (VIDD) in mechanically ventilated patients over time. Through measurements made even after mechanical ventilation (MV) it could be clarified to what extent patients recover from VIDD. Paired with cortical stimulation and electromyographic recordings of diaphragm muscle potentials, it could be explored to what extent decreased diaphragm excitability due to long term MV contributes to VIDD on the level of motor cortex. Against that background the present project aims at determining the rate of decline in diaphragm function, strength and control in patients undergoing MV (including measurements after extubation).

NCT ID: NCT03936920 Active, not recruiting - Clinical trials for Intensive Care (ICU) Myopathy

Intra and Inter Reliability and Validity of the Turkish Version of Ottowa Sitting Scale in Intensive Care Unit Survivors

Start date: February 13, 2019
Phase:
Study type: Observational

Introduction-Objective: Balance evaluation is one of the most important components of physical examination. Studies on equilibrium assessment in different research groups; It includes measurements that assess the seating balance, which does not require complex measurements or ambulation. In the literature, there is no clear information about balance effect in intensive care patients who can not be ambulated due to loss of advanced muscle strength, especially in the early period. Ottowa Sitting Scale is a scale in which the balance is evaluated in the sitting position and it has no validity and reliability in Turkish. Therefore, the aim of this study is to examine the reliability and validity of the Ottowa Sitting Scale Turkish version between measurements and measurements.

NCT ID: NCT03819959 Completed - Critical Illness Clinical Trials

Metabolomics Study on Intensive Care Acquired Muscle Weakness in Polytrauma

MIRACLE II
Start date: March 24, 2019
Phase:
Study type: Observational

In this mono-center pilot trial, polytrauma patients admitted to intensive care will be included. Investigators are going to take blood and muscle samples at respecified time points to do metabolic, histological and molecular testing. Aim of the study is to investigate (1) changes of the blood metabolome in patients with ICUAW (intensive care unit acquired weakness) and (2) identify metabolic components who are responsible for ICUAW or can be used as marker for ICUAW.

NCT ID: NCT03810768 Recruiting - Critical Illness Clinical Trials

Metabolomics Study on Postoperative Intensive Care Acquired Muscle Weakness

MIRACLE I
Start date: September 2, 2022
Phase:
Study type: Observational

In this mono-center pilot trial, surgical patients who are at high risk to be admitted to intensive care will be screened and asked for participation. We are going to take blood and muscle samples at respecified time points to do metabolic, histological and molecular testing. Aim of the study is to investigate (1) changes of the blood metabolome in patients with ICUAW (intensive care unit acquired weakness) and (2) identify metabolic components who are responsible for ICUAW or can be used as marker for ICUAW.

NCT ID: NCT03753412 Recruiting - Clinical trials for Acute Respiratory Distress Syndrome

Recovery From ICUAW Following Severe Respiratory and Cardiac Failure

CLEVERER
Start date: April 9, 2019
Phase:
Study type: Observational

To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO). Additionally, to discover the effects of ICUAW on physical function and health-related quality of life (HRQoL) after critical illness. CLEVERER is a clinical observational pilot study.

NCT ID: NCT03717831 Completed - Critical Illness Clinical Trials

Muscle Dysfunction in Critical Illness

Start date: October 17, 2018
Phase:
Study type: Observational

Patients surviving critical illness suffered significant skeletal muscle dysfunction and weakness that impacts their functionality and independence. The primary purpose of this project is to develop a classification system based on the health and function of the muscle at very early time points during critical illness. The investigators will determine if muscle ultrasound can predict functional recovery at six-months post hospital discharge. Researchers will assess muscle health and function from starting day one of admission to ICU and continue until six months of recovery. In addition to muscle ultrasound, the investigators will assess muscle strength and power, and perform muscle tissue analysis on a subset of individuals. These findings will be correlated to physical function and independence at six-month follow-up.

NCT ID: NCT03714399 Completed - Surgery Clinical Trials

Muscle Recovery Following Aortic Surgery Induced ICUAW.

VARIANCE
Start date: February 19, 2019
Phase:
Study type: Observational

To identify determinants of 'good and bad recovery' from ICUAW and build knowledge around the timing of these processes. Also, the investigators want to discover the effects of ICUAW on physical function and HRQoL following aortic surgery.

NCT ID: NCT03697785 Recruiting - Clinical trials for Respiratory Insufficiency

Weaning Algorithm for Mechanical VEntilation

WAVE
Start date: September 24, 2018
Phase: N/A
Study type: Interventional

To compare the duration of mechanical ventilation and the weaning period between two groups of patients managed with either Standard Care or with mechanical ventilation adjusted according to the Beacon Caresystem, in patients receiving mechanical ventilation for more than 24 hours

NCT ID: NCT03619915 Completed - Clinical trials for Intensive Care (ICU) Myopathy

Correlation Between Spirometry and Functional Independence in Adult Post-ICU Patients

Start date: January 2012
Phase:
Study type: Observational

Several complications and comorbidities are frequently found in patients admitted to an Intensive Care Unit (ICU), including acquired ICU muscle weakness and physical and cognitive limitations. These issues lead to impaired quality of life and post-discharge functional independence. Thus, it is important to evaluate these factors in order to verify the effects of long-term hospitalization. Objective: To relate functional independence to the degree of pulmonary involvement in adult patients three months after discharge from the ICU. Methods: This will be a retrospective study with data collected from January 2012 to December 2013, that will include patients who underwent spirometry and answered the Functional Independence Measure Questionnaire. Patients will be divided into groups according to the classification of functional independence and spirometry.