Modulating Energy Density in Time-Restricted Eating — MEDITRE  

Insulin Resistance Clinical Trial

Official title: Modulating Energy Density in Time-Restricted Eating

Status Recruiting

Clinical Trial Summary

The goal of this randomized controlled trial is to test the effect of time-restricted eating (14-hour fast, 10-hour eating window) of a low-energy dense diet (reduced calories per gram of food) in older adults with obesity and insulin resistance. The study aims to determine if modulating the energy density of the diet reduces:

1. Insulin resistance and

2. Body weight.

Researchers will compare the groups:

1. Following time-restricted eating and given a diet reduced in energy density or

2. Following time-restricted eating and given a diet typically consumed in this population

Clinical Trial Description

The study is an eight-week randomized controlled double-blinded clinical trial. Participants will follow time-restricted eating (14-hour fast, 10-hour eating window), and will be randomized to a diet low in energy density or the usual diet. Meals will be prepared in a metabolic kitchen and dispensed to participants. Dietitians will monitor dietary compliance. A blood sample will be drawn and body weight will be measured before starting the intervention and after completing it. ;

Related Conditions & MeSH terms

• Body Weight
• Insulin Resistance

• NCT number: NCT06259435
• Study type: Interventional
• Source: Pennington Biomedical Research Center
• Contact: Candida J Rebello, Ph.D.
• Phone: 2252882411
• Email: Candida.Rebello@pbrc.edu
• Status: Recruiting
• Phase: N/A
• Start date: May 29, 2024
• Completion date: December 2025