Effect of Whole-body Vibration on Insulin Resistance in Obese Postmenopausal Women.

Insulin Resistance Clinical Trial

Official title:

Effect of Whole-body Vibration on Insulin Resistance in Obese Postmenopausal Women.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05961020
• Other study ID #: p.t.REC\012\004551
• Status: Completed
• Phase: N/A
• Start date: November 5, 2022
• Est. completion date: July 8, 2023

Study information

• Verified date: May 2024
• Source: October 6 University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study will be conducted to investigate the Effect of whole-body vibration on insulin resistance in obese postmenopausal women

Description:

The prevalence of obesity has tripled over the past four decades, imposing an enormous burden on people's health.

Obesity is associated with premature mortality and is a serious public health threat that accounts for a large proportion of the worldwide non-communicable disease burden, including type 2 diabetes, cardiovascular disease, hypertension, and certain cancers.

reported that "Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system. Therefore, in this study, The aim to investigate the effect of whole-body vibration on insulin resistance in obese postmenopausal.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 40
• Est. completion date: July 8, 2023
• Est. primary completion date: January 3, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 50 Years to 60 Years

Eligibility

Inclusion Criteria:

• All women were postmenopausal with no menses at least 1 year.

• Their ages were ranged from 50-60 years old.

• Their body mass index (BMI) > 30 kg/m2.

• They were not engaged in any other treatment program.

Exclusion Criteria:

• Women with body mass index (BMI) < 30 kg/m2.

• Any cardio-respiratory diseases.

• Diabetes mellitus.

• with malignancy.

• with severe hemorrhage, acute viral disease and mental disorders.

• Smokers.

• Women with life threatening disorders as renal failure

Related Conditions & MeSH terms

• Insulin Resistance

Intervention

Device:
• Total body vibration
Whole-body vibration (WBV) training has been established as a useful method to improve physical fitness in obese individuals. Vibration stimulus during half squatting might suggest a long-term effect of WBV on the endocrine system

Other:
• moderate restricted diet
moderate restricted diet

Locations

Country	Name	City	State
Egypt	Kerolous Ishak Shehata kelini	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
October 6 University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The Homeostatic model assessment (The HOMA-IR).	The Homeostatic model assessment (The HOMA-IR).; A sample of 5ml of venous blood sample was drawn from all women after 12 hours fasting for measurement of fasting blood glucose, fasting blood insulin and then detection of insulin resistance (by HOMA -IR) through the equation: HOMA-IR=(Glucose ×Insulin)/405 glucose in mass unit (mg/dl)	up to 3 months
Primary	BMI	Weight and height were measured to detect the BMI according to the following equation: BMI= weight/height² (Kg/m²)	up to 3 months
Primary	Waist circumference	A non-stretchable tape measurement was used to measure waist circumference for all women in both groups A and B: mid-way between upper border of the lateral iliac crest and the lower border of the lowest rib at the end of gentle expiration with arm relaxed at sides.	up to 3 months
Primary	Skin fold thickness	Skin fold caliper was used to measure skin fold thickness at abdominal region for all women in both groups A and B	up to 3 months