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Evaluating the Effect of Inositol Supplementation in Overweight Children on Basal Insulin and Body Weight

Insulin Resistance Clinical Trial

Official title:
Effects of Inositol Supplementation in Children With Excessive Body Weight and Insulin Resistance

Clinical Trial Summary

Inositol in involved in the insulin pathway. In literature it has been demonstrated to improve insulin sensitivity and ovarian function in women affected by PCOS.

In a preliminary study conducted on obese children between 7 and 15 years, the investigators have demonstrated that Inositol administration (Myo-inositol 1100 mg + D-Chiro-inositol 27,6 mg + Folic Acid 400 μg) before a Glucose Oral Tolerance Test reduces the increase of insulin levels, particularly in subjects with basal insulin ≥ 15 uU/ml.

So the aim of this study is to evaluate the potential therapeutic effect of inositol, as non-pharmacologic agent, in preventing tipe II diabetes in children.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03920787
Study type Interventional
Source Azienda Ospedaliera San Paolo
Contact Mario Mancini
Phone 00393331009479
Email mancinis178@msn.com
Status Recruiting
Phase N/A
Start date March 10, 2018
Completion date April 2020
View Details
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