The Effect of Tea on Vascular Function and Insulin Sensitivity

Insulin Resistance Clinical Trial

Official title: Can Tea Prevent Impairments in Vascular Function and Insulin Sensitivity Induced by 7-days Physical Inactivity and Overfeeding in Healthy Men

Status Completed

Clinical Trial Summary

The aim of this research is to explore changes in peripheral/cerebrovascular function and insulin sensitivity after a 7-day combination of physical activity reduction (-50% steps per day) and overfeeding (+50% kcal per day, comprising 65% fat) in healthy male volunteers, and examine whether daily intake of tea can prevent such changes.

Clinical Trial Description

The aim of this study is to explore the impact of a 7-day 'unhealthy' lifestyle that combines physical activity reduction (-50% steps per day) and overfeeding (+50% kcal per day, comprising 65% fat) on peripheral (conduit artery and skin microvessels) and cerebrovascular function and insulin sensitivity in healthy male participants. Moreover, the investigators will explore whether the detrimental impact of this lifestyle can be mitigated by daily tea consumption (equivalent to 6 cups/day). To explore this hypothesis, the investigators will perform measurements of these parameters before and after 7-days of reduced physical activity and overfeeding, with and without the combination of daily tea ingestion. ;

Related Conditions & MeSH terms

• Hypersensitivity
• Insulin Resistance

• NCT number: NCT02777853
• Study type: Interventional
• Source: Liverpool John Moores University
• Status: Completed
• Phase: N/A
• Start date: May 2016
• Completion date: July 2017